Results 1 to 10 of about 987,804 (362)

Open-source genomic analysis of Shiga-toxin–producing E. coli O104:H4 [PDF]

, 2011
An outbreak caused by Shiga-toxin–producing Escherichia coli O104:H4 occurred in Germany in May and June of 2011, with more than 3000 persons infected. Here, we report a cluster of cases associated with a single family and describe an open-source genomic
Antoine Danchin, Cordesmeyer S, Dongfang Li, Fei Pu, Feng Xi, George F. Gao, Holger Rohde, Huanming Yang, Itoh Y, Jian Wang, Jianguo Xu, Jun Oh, Jun Wang, Junhua Li, Junjie Qin, Kuijper E, Liang Yang, Mark J. Pallen, Martin Aepfelbacher, Martin Christner, Meiru Zhao, Moritz Hentschke, Nicholas J. Loman, Peng Wang, Robin Kobbe, Ruifu Yang, Scheutz F, Sebastian Loos, Shenghui Li, Wentong Chen, Xiangna Zhao, Xianwei Yang, Yajun Song, Yangqing Peng, Yin Li, Yingrui Li, Yuanlin Guan, Yujun Cui, Zhaoxi Zhang, Zhong Cen   +39 more
core   +1 more source

Porcine Colostrum Protects the IPEC-J2 Cells and Piglet Colon Epithelium against Clostridioides (syn. Clostridium) difficile Toxin-Induced Effects [PDF]

, 2020
Clostridioides difficile toxins are one of the main causative agents for the clinical symptoms observed during C. difficile infection in piglets. Porcine milk has been shown to strengthen the epithelial barrier function in the piglet’s intestine and may ...
Grześkowiak, Łukasz, Hauser, Anja E., Kröger, Susan, Martínez-Vallespín, Beatriz, Niesner, Raluca, Pieper, Robert, Vahjen, Wilfried, Zentek, Jürgen   +7 more
core   +1 more source

Assessment of the Adjuvant Effects of Lentinan on the Tuberculosis Subunit Vaccine BG

Vaccines
Objectives: This study aims to assess the adjuvant effects of lentinan and its combination with Mn(J), a manganese-based colloidal adjuvant, on the BG (fusion protein BfrB-GrpE of Mycobacterium tuberculosis) subunit vaccine.
Shuai Zhou, Yilin Hou, Xiaojuan Zhang, Zhuoxuan Lv, Quanjie Hu, Xiaobing Yang, Hongxia Niu   +6 more
doaj   +1 more source

Use of Monoclonal Antibodies in the Sensitive Detection and Neutralization of Botulinum Neurotoxin Serotype B

Toxins, 2015
Botulinum neurotoxins (BoNT) are some of nature’s most potent toxins. Due to potential food contamination, and bioterrorism concerns, the development of detection reagents, therapeutics and countermeasures are of urgent interest.
Luisa W. Cheng, Thomas D. Henderson, Tina I. Lam, Larry H. Stanker   +3 more
doaj   +1 more source

Qualitative comparison of cassiicolin in four strains of Corynespora cassiicola [PDF]

, 2008
Corynespora cassiicola is a necrotrophic ascomycete fungus affecting a wide range of plants. In rubber tree, C. cassiicola causes the Corynespora Leaf Fall (CLF) disease, responsible for sporadic but often severe epidemics in rubber plantations in most ...
Bieysse, Daniel, Bourre, Yanice, De Lamotte, Frédéric, Poncet, Julie, Pujade-Renaud, Valérie   +4 more
core  

The envenomation of general physiology throughout the last century. [PDF]

, 2017
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
core   +1 more source

Influence of Food Matrices on the Stability and Bioavailability of Abrin

Toxins, 2018
Abrin, a highly toxic plant toxin, is a potential bioterror weapon. Work from our laboratory and others have shown that abrin is highly resistant to both thermal and pH inactivation methods.
Christina C. Tam, Thomas D. Henderson, Larry H. Stanker, Luisa W. Cheng   +3 more
doaj   +1 more source

Development and Characterization of Monoclonal Antibodies to Botulinum Neurotoxin Type E

Toxins, 2019
Botulism is a devastating disease caused by botulinum neurotoxins (BoNTs) secreted primarily by Clostridium botulinum. Mouse bioassays without co-inoculation with antibodies are the standard method for the detection of BoNTs, but are not capable of ...
Candace S. Bever, Miles Scotcher, Luisa W. Cheng, Robert M. Hnasko, Larry H. Stanker   +4 more
doaj   +1 more source

Antifungal Drug Repurposing

Antibiotics, 2020
Control of fungal pathogens is increasingly problematic due to the limited number of effective drugs available for antifungal therapy. Conventional antifungal drugs could also trigger human cytotoxicity associated with the kidneys and liver, including ...
Jong H. Kim, Luisa W. Cheng, Kathleen L. Chan, Christina C. Tam, Noreen Mahoney, Mendel Friedman, Mikhail Martchenko Shilman, Kirkwood M. Land   +7 more
doaj   +1 more source

Proteomic Profiling of Venoms from Bungarus suzhenae and B. bungaroides: Enzymatic Activities and Toxicity Assessment

Toxins
Kraits are venomous snakes of the genus Bungarus from the family Elapidae. Their venom typically demonstrates neurotoxicity; however, the toxicity is significantly influenced by the snake’s species and geographical origin.
Chenying Yang, Li Ding, Qiyi He, Xiya Chen, Haiting Zhu, Feng Chen, Wanzhou Yang, Yuexin Pan, Zhiyuan Tai, Wenhao Zhang, Zeyuan Yu, Zening Chen, Xiaodong Yu   +12 more
doaj   +1 more source