Results 11 to 20 of about 880,943 (314)

Structural insights into Clostridium perfringens delta toxin pore formation [PDF]

open access: yes, 2013
Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
AGW Leslie   +57 more
core   +13 more sources

Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]

open access: yes, 1990
The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Dayanithi, G.   +4 more
core   +6 more sources

T-cell receptor Vβ8 for detection of biologically active streptococcal pyrogenic exotoxin type C

open access: yesJournal of Dairy Science, 2023
: Streptococcus pyogenes is an important human pathogen, commonly spread by airborne droplets but also by ingestion of contaminated food. Apart from causing infection, this pathogen produces 13 distinct types of streptococcal pyrogenic exotoxins (SPE ...
Reuven Rasooly   +2 more
doaj   +1 more source

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement [PDF]

open access: yes, 1980
Lysosomotropic amines, such as ammonium chloride, are known to protect cells from the cytotoxic effects of diphtheria toxin. These drugs are believed to inhibit the transport of the toxin from a receptor at the cell exterior into the cytoplasm where a ...
Draper, Rockford K., Simon, Melvin I.
core   +2 more sources

Human Leukemia T-Cell Lines as Alternatives to Animal Use for Detecting Biologically Active Staphylococcal Enterotoxin Type B

open access: yesToxins, 2021
Staphylococcal enterotoxin type B (SEB) is associated with food poisoning. Current methods for the detection of biologically active SEB rely upon its ability to cause emesis when administered to live kittens or monkeys.
Reuven Rasooly   +3 more
doaj   +1 more source

Botulinum toxin

open access: yesIndian Journal of Dermatology, 2010
Botulinum toxin, one of the most poisonous biological substances known, is a neurotoxin produced by the bacterium Clostridium botulinum. C. botulinum elaborates eight antigenically distinguishable exotoxins (A, B, C(1), C(2), D, E, F and G). All serotypes interfere with neural transmission by blocking the release of acetylcholine, the principal ...
Nigam P, Nigam Anjana
openaire   +3 more sources

Characterizing RecA-Independent Induction of Shiga toxin2-encoding Phages by EDTA Treatment [PDF]

open access: yes, 2013
The bacteriophage life cycle has an important role in Shiga toxin (Stx) expression. The induction of Shiga toxin-encoding phages (Stx phages) increases toxin production as a result of replication of the phage genome, and phage lysis of the host cell also
Imamovic, Lejla   +1 more
core   +2 more sources

Cervical dystonia: non-motor aspects

open access: yesНеврология, нейропсихиатрия, психосоматика, 2020
Cervical dystonia (CD) is manifested by violent, often painful movements of the neck muscles with the abnormal head and/or neck postures being formed. Disease progression leads to disability of patients.
O. A. Druzhinina   +3 more
doaj   +1 more source

Liquid chromatography-tandem mass spectrometry analysis of a ratio-optimized drug pair of Sophora flavescens Aiton and Coptis chinensis Franch and study on the mechanism of anti-colorectal cancer effect of two alkaloids thereof

open access: yesFrontiers in Oncology, 2023
The drug pair consisting of Sophora flavescens Aiton (Sophorae flavescentis radix, Kushen) and Coptis chinensis Franch. (Coptidis rhizoma, Huanglian), as described in Prescriptions for Universal Relief (Pujifang), is widely used to treat laxation ...
Zihan Chen   +14 more
doaj   +1 more source

Comparative pathogenomic analysis reveals a highly tetanus toxin-producing clade of Clostridium tetani isolates in Japan

open access: yesmSphere, 2023
Clostridium tetani is the etiological agent of the disease tetanus, resulting in various symptoms, including neck tension, tongue-twisting, a decline in walking ability, and death in severe cases. To date, publicly available genome sequences of C. tetani
Chie Shitada   +6 more
doaj   +1 more source

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