Results 101 to 110 of about 25,002 (218)
Phenotypic responses to interspecies competition and commensalism in a naturally derived microbial co-culture [PDF]
, 2018 The fundamental question of whether different microbial species will co-exist or compete in a given environment depends on context, composition and environmental constraints.
Barney, Brett M. +11 more
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Identification and characterization of a toxin-antitoxin system in the pVir plasmid of Campylobacter jejuni [PDF]
, 2011 Toxin-antitoxin systems are prevalent in different bacterial organisms and are encoded in the chromosomal or plasmid DNA. The primary function of a plasmid toxin-antitoxin module is to stabilize the plasmid by eliminating plasmid-free daughter cells ...
Patil, Rocky Damodar
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Plant Biotechnology Journal, Volume 23, Issue 6, Page 2386-2399, June 2025.Summary Apple (Malus domestica Borkh.) is a globally significant crop and a vital dietary component worldwide. During ripening, apples exhibit a longitudinal gradient, ripening first at the stalk cavity and extending towards the calyx concave. When the fruit is harvested at the right time or later, the stalk cavity of many varieties often shows over ...
Hui Wang +6 more
wiley +1 more source
Regulating Toxin-Antitoxin Expression: Controlled Detonation of Intracellular Molecular Timebombs
Toxins, 2014 Genes for toxin-antitoxin (TA) complexes are widely disseminated in bacteria, including in pathogenic and antibiotic resistant species. The toxins are liberated from association with the cognate antitoxins by certain physiological triggers to impair ...
Finbarr Hayes, Barbara Kędzierska
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The bacterial Type III toxin-antitoxin system, ToxIN, is a dynamic protein-RNA complex with stability-dependent antiviral abortive infection activity. [PDF]
, 2018 Bacteria have evolved numerous defense systems to protect themselves from viral (bacteriophage) infection. The ToxIN system of Pectobacterium atrosepticum is a Type III toxin-antitoxin complex and "altruistic suicide" anti-phage system, which kills phage-
Akusobi, Chidiebere +3 more
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FEBS Letters, Volume 599, Issue 9, Page 1222-1235, May 2025.The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet +4 more
wiley +1 more source
Novel Single-Cell Method for Studying Toxin-Antitoxin Systems [PDF]
, 2016 细菌的抗药性危害日益严重，毒素－抗毒素（TA）系统在细菌内的异质性表达是多药耐受性存留细胞形成的重要原因。阐明致病菌中毒素－抗毒素系统的作用机理和生理功能对研发防控致病菌的新策略和疾病诊断治疗等具有重要意义。目前，对TA系统的研究主要集中在基因水平或转录水平，而传统基于蛋白质水平的检测方法，如WesternBlot等都是对大量细菌裂解液中的毒素抗毒素蛋白进行检测，是大量细菌内毒素抗毒素蛋白表现的集权平均。对单细菌水平的毒素－抗毒素蛋白进行快速逐一分析可揭示因集权平均而被掩盖的个体差异 ...
宋毅怡
core
Shaping Pulses to Control Bistable Biological Systems [PDF]
, 2015 In this paper we study how to shape temporal pulses to switch a bistable system between its stable steady states. Our motivation for pulse-based control comes from applications in synthetic biology, where it is generally difficult to implement real-time ...
Angeli, David +3 more
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A competence-regulated toxin-antitoxin system in Haemophilus influenzae.
PLoS ONE, 2020 Natural competence allows bacteria to respond to environmental and nutritional cues by taking up free DNA from their surroundings, thus gaining both nutrients and genetic information.
Hailey Findlay Black +6 more
doaj +1 more source
Toxin-Antitoxin Flocculation in Tetanus
Experimental Biology and Medicine, 1936 While the flocculation-test with diphtheria-toxin and antitoxin has given fairly good results,1, 2 the method has been found unreliable when applied to toxins and respective antitoxins of tetanus,3, 4, 5 botulinus,6, 7 staphylococcus,8 and Streptococcus scarlatinœ.9, 10Bronfenbrenner and Reichert6 found that antitoxin obtained by immunizing animals ...
openaire +2 more sources