The coevolution of toxin and antitoxin genes drives the dynamics of bacterial addiction complexes and intragenomic conflict [PDF]
, 2012 Bacterial genomes commonly contain ‘addiction’ gene complexes that code for both a toxin and a corresponding antitoxin. As long as both genes are expressed, cells carrying the complex can remain healthy.
Brown, Sam P. +3 more
core +1 more source
The vapB-vapC operon of Acidovorax citrulli functions as a bona-fide toxin-antitoxin module
Frontiers in Microbiology, 2016 Toxin–antitoxin systems are commonly found on plasmids and chromosomes of bacteria and archaea. These systems appear as biscystronic genes encoding a stable toxin and a labile antitoxin, which protects the cells from the toxin’s activity. Under specific,
Reut eShavit +4 more
doaj +1 more source
Escherichia coli EHEC Germany outbreak preliminary functional annotation using BG7 system [PDF]
, 2011 We have annotated the European outbreak E. coli EHEC genome sequenced by BGI (6-2-2011) and assembled with MIRA by Nick Loman (6-2-2011 ). Our system BG7, Bacterial Genome annotation of Era7 Bioinformatics, predicts ORFs and annotates them based on ...
Eduardo Pareja +4 more
core +2 more sources
Small Open Reading Frames, Non-Coding RNAs and Repetitive Elements in Bradyrhizobium japonicum USDA 110 [PDF]
, 2016 Small open reading frames (sORFs) and genes for non-coding RNAs are poorly investigated components of most genomes. Our analysis of 1391 ORFs recently annotated in the soybean symbiont Bradyrhizobium japonicum USDA 110 revealed that 78% of them contain ...
Cuklina, Jelena +5 more
core +2 more sources
Toxin–antitoxin systems: reversible toxicity
Current Opinion in Microbiology, 2017 Toxin-antitoxin (TA) systems encoded on the plasmids and chromosomes of bacteria are emerging as key players in stress adaptation. In particular, they have been implicated in the induction of persisters non-growing cells that can evade antibiotic exposure.
Hall, A, Gollan, B, Helaine, S
openaire +5 more sources
Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates [PDF]
, 2012 The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and non-pneumococcal streptococci from Denmark, the Gambia, the Netherlands, Thailand, the
Antonio, M +10 more
core +1 more source
Complete Assembly of the Genome of an Acidovorax citrulli Strain Reveals a Naturally Occurring Plasmid in This Species [PDF]
, 2019 Acidovorax citrulli is the causal agent of bacterial fruit blotch (BFB), a serious threat to cucurbit crop production worldwide. Based on genetic and phenotypic properties, A.
Chen, Gong +6 more
core +1 more source
Frontiers in Microbiology, 2020 Salmonella enterica serotype Typhimurium is a bacterium that causes gastroenteritis and diarrhea in humans. The genome of S. Typhimurium codes for diverse virulence factors, among which are the toxin-antitoxin (TA) systems.
Fernando Chimal-Cázares +14 more
doaj +1 more source
The Bacillus cereus spoIIS programmed cell death system
Frontiers in Microbiology, 2015 Programmed cell death in bacteria is generally associated with two¬ component toxin antitoxin systems. The SpoIIS toxin-antitoxin system, consisting of a membrane bound SpoIISA toxin and a small, cytosolic antitoxin SpoIISB, was originally identified in ...
Jana eMelnicakova +3 more
doaj +1 more source
Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains [PDF]
, 2013 UNLABELLED: In this work, we show that Clostridium difficile phage ϕC2 transduces erm(B), which confers erythromycin resistance, from a donor to a recipient strain at a frequency of 10(-6) per PFU.
Chang, Barbara J +5 more
core +2 more sources