Results 51 to 60 of about 25,002 (218)
THE NATURE OF THE TOXIN-ANTITOXIN FLOCCULATION PHENOMENON [PDF]
Journal of Experimental Medicine, 1926 1. Animals immunized with the formalinized filtrates of young toxic cultures of B. botulinus produce an antitoxic serum poor in precipitins. 2. Animals immunized with the formalinized filtrates of old and partly autolyzed toxic cultures produce an antitoxic serum containing precipitins. 3. Animals immunized with toxin-free
Philip Reichert, J. Bronfenbrenner
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Structural insights into chaperone addiction of toxin-antitoxin systems
Nature Communications, 2019 SecB homologs can be associated with stress-responsive type II toxin–antitoxin (TA) systems and form tripartite toxin-antitoxin-chaperone systems (TAC).
Valérie Guillet +12 more
doaj +1 more source
Geometric Properties of Isostables and Basins of Attraction of Monotone Systems [PDF]
, 2017 In this paper, we study geometric properties of basins of attraction of monotone systems. Our results are based on a combination of monotone systems theory and spectral operator theory.
Mauroy, Alexandre, Sootla, Aivar
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Advanced Science, EarlyView.Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang +8 more
wiley +1 more source
Toxin-Antitoxin Systems and Persistence
, 2019 Toxin-antitoxin (TA) systems are small genetic modules comprising a stable toxic protein and an antitoxin preventing the toxin activity. In type II TA systems, antitoxins are unstable proteins that are degraded by host ATP-dependent proteases. In steady-state conditions, the antitoxin forms a complex with the toxin in which the toxic activity is ...
Fraikin, Nathan +2 more
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TOXIN-ANTITOXIN IMMUNIZATION AGAINST DIPHTHERIA [PDF]
JAMA: The Journal of the American Medical Association, 1922 The development of antitoxin in the bodies of animals injected with diphtheria toxin is one of the best established of facts. Since von Behring and Roux announced the results of their investigations, large numbers of horses have been injected with toxin and have developed abundant antitoxin.
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Observations on the preparation of toxin-antitoxin mixture [PDF]
Journal of Infectious Diseases, 1922 Immunization against diphtheria by toxin-antitoxin has been eminently successful, and this means that another milestone has been passed in the efforts to eradicate the disease. Successful immunization depends on proper balance of toxin and antitoxin.
Heineman, P. G., Hixson, C. R.
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Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Toxin-Antitoxin Pairs in Bacteria [PDF]
Cell, 2003 Plasmid toxin-antitoxin systems, which kill daughter cells that fail to inherit the plasmid genome, have chromosomal homologs in eubacteria and archaea. In this issue of Cell, Pederson et al. show that the E. coli RelE toxin cleaves mRNA in the ribosomal A site, potentially allowing it to function as a stress regulator during amino acid starvation.
Christopher S. Hayes, Robert T. Sauer
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BMC Genomics, 2006 Background Post-segregational killing systems are present in a large variety of microorganisms. When found on plasmids, they are described as addiction systems that act to maintain the plasmid during the partitioning of the cell.
Mahillon Jacques, Fico Sarah
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