Results 51 to 60 of about 24,156 (244)
Expression, Purification, and Functional Analysis of Novel RelE Operon from X. nematophila
The Scientific World Journal, 2014 Bacterial toxin-antitoxin (TA) complexes induce programmed cell death and also function to relieve cell from stress by various response mechanisms. Escherichia coli RelB-RelE TA complex consists of a RelE toxin functionally counteracted by RelB antitoxin.
Jitendra Singh Rathore +1 more
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Shaping Pulses to Control Bistable Monotone Systems Using Koopman Operator [PDF]
, 2016 In this paper, we further develop a recently proposed control method to switch a bistable system between its steady states using temporal pulses. The motivation for using pulses comes from biomedical and biological applications (e.g.
Goncalves, Jorge +2 more
core +2 more sources
PLoS Genetics, 2020 RHS elements are components of conserved toxin-delivery systems, wide-spread within the bacterial kingdom and some of the most positively selected genes known. However, very little is known about how Rhs toxins affect bacterial biology.
Magnus Stårsta +8 more
doaj +1 more source
Geometric Properties of Isostables and Basins of Attraction of Monotone Systems [PDF]
, 2017 In this paper, we study geometric properties of basins of attraction of monotone systems. Our results are based on a combination of monotone systems theory and spectral operator theory.
Mauroy, Alexandre, Sootla, Aivar
core +3 more sources
Evaluating the Potential for Cross-Interactions of Antitoxins in Type II TA Systems
Toxins, 2020 The diversity of Type-II toxin–antitoxin (TA) systems in bacterial genomes requires tightly controlled interaction specificity to ensure protection of the cell, and potentially to limit cross-talk between toxin–antitoxin pairs of the same family of TA ...
Chih-Han Tu +3 more
doaj +1 more source
Bacterial type I toxin-antitoxin systems [PDF]
RNA Biology, 2012 Toxin-antitoxin (TA) loci encode two-component systems that consist of a stable "toxin" whose ectopic overexpression either kills cells or confers growth stasis, and an unstable "antitoxin". TA systems have been initially discovered on plasmids, where they confer stability of maintenance through post-segregational killing (PSK). Plasmid loss results in
openaire +2 more sources
Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]
, 1990 The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Ahnert-Hilger, G. +4 more
core +1 more source
PLoS Genetics, 2012 Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal population, can be mediated by toxin-antitoxin systems such as the Type III protein-RNA toxin-antitoxin
Tim R Blower +4 more
doaj +1 more source
Bacterial toxin-antitoxin systems targeting translation [PDF]
Journal of Applied Biomedicine, 2010 10 p.-2 fig. Toxin-antitoxin systems (TAS) emerged more than 25 years ago and have since developed as an important field in molecular microbiology. TAS are autoregulated operons coding a stable toxin and an unstable antitoxin found in the plasmids and chromosomes of Bacteria and Archaea.
Díaz-Orejas, Ramón +7 more
openaire +2 more sources
AAU-Specific RNA Cleavage Mediated by MazF Toxin Endoribonuclease Conserved in Nitrosomonas europaea
Toxins, 2016 Nitrosomonas europaea carries numerous toxin-antitoxin systems. However, despite the abundant representation in its chromosome, studies have not surveyed the underlying molecular functions in detail, and their biological roles remain enigmatic.
Tatsuki Miyamoto +3 more
doaj +1 more source