Results 61 to 70 of about 23,162 (212)

The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]

open access: yes, 2008
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Al Madani   +37 more
core   +1 more source

Evaluating the Potential for Cross-Interactions of Antitoxins in Type II TA Systems

open access: yesToxins, 2020
The diversity of Type-II toxin–antitoxin (TA) systems in bacterial genomes requires tightly controlled interaction specificity to ensure protection of the cell, and potentially to limit cross-talk between toxin–antitoxin pairs of the same family of TA ...
Chih-Han Tu   +3 more
doaj   +1 more source

Bacterial type I toxin-antitoxin systems [PDF]

open access: yesRNA Biology, 2012
Toxin-antitoxin (TA) loci encode two-component systems that consist of a stable "toxin" whose ectopic overexpression either kills cells or confers growth stasis, and an unstable "antitoxin". TA systems have been initially discovered on plasmids, where they confer stability of maintenance through post-segregational killing (PSK). Plasmid loss results in
openaire   +2 more sources

Viral evasion of a bacterial suicide system by RNA-based molecular mimicry enables infectious altruism.

open access: yesPLoS Genetics, 2012
Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal population, can be mediated by toxin-antitoxin systems such as the Type III protein-RNA toxin-antitoxin
Tim R Blower   +4 more
doaj   +1 more source

RHS-elements function as type II toxin-antitoxin modules that regulate intra-macrophage replication of Salmonella Typhimurium.

open access: yesPLoS Genetics, 2020
RHS elements are components of conserved toxin-delivery systems, wide-spread within the bacterial kingdom and some of the most positively selected genes known. However, very little is known about how Rhs toxins affect bacterial biology.
Magnus Stårsta   +8 more
doaj   +1 more source

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates [PDF]

open access: yes, 2012
The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and non-pneumococcal streptococci from Denmark, the Gambia, the Netherlands, Thailand, the
Antonio, M   +10 more
core   +1 more source

Bacterial toxin-antitoxin systems targeting translation [PDF]

open access: yesJournal of Applied Biomedicine, 2010
10 p.-2 fig. Toxin-antitoxin systems (TAS) emerged more than 25 years ago and have since developed as an important field in molecular microbiology. TAS are autoregulated operons coding a stable toxin and an unstable antitoxin found in the plasmids and chromosomes of Bacteria and Archaea.
Díaz-Orejas, Ramón   +7 more
openaire   +2 more sources

AAU-Specific RNA Cleavage Mediated by MazF Toxin Endoribonuclease Conserved in Nitrosomonas europaea

open access: yesToxins, 2016
Nitrosomonas europaea carries numerous toxin-antitoxin systems. However, despite the abundant representation in its chromosome, studies have not surveyed the underlying molecular functions in detail, and their biological roles remain enigmatic.
Tatsuki Miyamoto   +3 more
doaj   +1 more source

The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence [PDF]

open access: yes, 2014
Nearly all bacteria exhibit a type of phenotypic growth described as persistence that is thought to underlie antibiotic tolerance and recalcitrant chronic infections.
Behiels, Ester   +6 more
core   +2 more sources

Toxin-Antitoxin Systems and Persistence

open access: yes, 2019
Toxin-antitoxin (TA) systems are small genetic modules comprising a stable toxic protein and an antitoxin preventing the toxin activity. In type II TA systems, antitoxins are unstable proteins that are degraded by host ATP-dependent proteases. In steady-state conditions, the antitoxin forms a complex with the toxin in which the toxic activity is ...
Fraikin, Nathan   +2 more
openaire   +2 more sources

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