Transcriptional control of the bacterial toxin-antitoxin system TimP-TimR [PDF]
, 2022 To survive in a constantly changing environment, bacteria need to adapt their lifestyle. They need mechanisms to regulate their growth rate, both in response to nutrient availability, but also to protect themselves against toxic compounds, including ...
Orrenius, Cecilia
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The DarTG toxin-antitoxin system provides phage defense by ADP-ribosylating viral DNA [PDF]
, 2023 Raw images for "The DarTG toxin-antitoxin system provides phage defense by ADP-ribosylating viral DNA"
LeRoux, M
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Expression, Purification, and Functional Analysis of Novel RelE Operon from X. nematophila
The Scientific World Journal, 2014 Bacterial toxin-antitoxin (TA) complexes induce programmed cell death and also function to relieve cell from stress by various response mechanisms. Escherichia coli RelB-RelE TA complex consists of a RelE toxin functionally counteracted by RelB antitoxin.
Jitendra Singh Rathore +1 more
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PLoS Genetics, 2020 RHS elements are components of conserved toxin-delivery systems, wide-spread within the bacterial kingdom and some of the most positively selected genes known. However, very little is known about how Rhs toxins affect bacterial biology.
Magnus Stårsta +8 more
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PLoS Genetics, 2012 Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal population, can be mediated by toxin-antitoxin systems such as the Type III protein-RNA toxin-antitoxin
Tim R Blower +4 more
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Evaluating the Potential for Cross-Interactions of Antitoxins in Type II TA Systems
Toxins, 2020 The diversity of Type-II toxin–antitoxin (TA) systems in bacterial genomes requires tightly controlled interaction specificity to ensure protection of the cell, and potentially to limit cross-talk between toxin–antitoxin pairs of the same family of TA ...
Chih-Han Tu +3 more
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To be or not to be: regulation of restriction–modification systems and other toxin–antitoxin systems [PDF]
Nucleic Acids Research, 2013 One of the simplest classes of genes involved in programmed death is that containing the toxin-antitoxin (TA) systems of prokaryotes. These systems are composed of an intracellular toxin and an antitoxin that neutralizes its effect. These systems, now classified into five types, were initially discovered because some of them allow the stable ...
Iwona Mruk, Kobayashi, Ichizo
openaire +2 more sources
AAU-Specific RNA Cleavage Mediated by MazF Toxin Endoribonuclease Conserved in Nitrosomonas europaea
Toxins, 2016 Nitrosomonas europaea carries numerous toxin-antitoxin systems. However, despite the abundant representation in its chromosome, studies have not surveyed the underlying molecular functions in detail, and their biological roles remain enigmatic.
Tatsuki Miyamoto +3 more
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Characterization of a Streptococcus mutans intergenic region containing a small toxic peptide and its cis-encoded antisense small RNA antitoxin. [PDF]
PLoS ONE, 2013 Toxin-antitoxin (TA) modules consist of a pair of genes that encode two components: a protein toxin and an antitoxin, which may be in the form of either a labile protein or an antisense small RNA. Here we describe, to the best of our knowledge, the first
Stephanie Koyanagi, Céline M Lévesque
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Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin
mBio, 2023 A type II VapB14 antitoxin regulates biofilm dispersal in the archaeal thermoacidophile Sulfolobus acidocaldarius through traditional toxin neutralization but also through noncanonical transcriptional regulation.
April M. Lewis +5 more
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