Results 201 to 210 of about 987,804 (362)

Neutralization of toxic shock syndrome toxin-1 by monoclonal antibodies in vitro and in vivo [PDF]

, 1988
Peter F. Bonventre, Michael R. Thompson, Luigi Elio Adinolfi, Z A Gillis, Julie Parsonnet   +4 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Stepwise assembly of α-hemolysin from intermediates to the mature pore in native erythrocytes. [PDF]

J Cell Biol
Chatterjee A, Roy A, Das PP, Chakraborty D, Ghoshal B, Jhunjhunwala S, Dutta S.   +6 more
europepmc   +1 more source

Variants of Hemagglutinin-33 in the Serotype C Botulinum Progenitor Toxin Complex Boost its Oral Toxicity

, 2022
Shura Karatsu, Shin-Ichiro Miyashita, Mitsuyoshi Hirokawa, I-Hsun Huang, Keita Hosoya, Yoshimasa Sagane   +5 more
openalex   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

ToxIR: an accurate RNA-seq pipeline for high-precision toxin transcriptome profiling, validated in odontobuthus doriae venom glands. [PDF]

Sci Rep
Ebadi M, Soorki MN.
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Bistability in type I toxin-antitoxin systems may lead to stress-induced persister formation. [PDF]

NPJ Syst Biol Appl
Markovic S, Djordjevic M, Ou HY, Djordjevic M.   +3 more
europepmc   +1 more source

The therapeutic use of botulinum toxin in cervical and maxillofacial conditions [PDF]

, 2009
K. Gadhia, A. D. Walmsley
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source