Results 211 to 220 of about 642,336 (319)

<i>Actinobacillus pleuropneumoniae</i> in Korea (2015-2025): serovar distribution, toxin gene profiles, antimicrobial resistance, and identification of an apxIICA-deficient serovar 15 profile. [PDF]

J Vet Sci
Bae DY, Kang EJ, Cho YC, Lim Y, Moon SH, Kim WI, Oh Y, Cho HS.   +7 more
europepmc   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Botulinum neurotoxin: from molecular pathogenesis to emerging countermeasures. [PDF]

Saudi Pharm J
Almudimeegh S.
europepmc   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Ribosomal RNA cleavage by the previously unidentified RelS-RelI toxin-antitoxin system controls growth of Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Han X, Arrowsmith TJ, Karamycheva S, Xu X, Coddeville M, Pagès C, Voisin B, Gutierrez C, Neyrolles O, Makarova KS, Blower TR, Genevaux P.   +11 more
europepmc   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

The Role of the Gut Microbiota and Uraemic Toxins in Vaccine Responsiveness Among People Receiving Maintenance Haemodialysis. [PDF]

Vaccines (Basel)
Vaughan E, Gilbert A, Shi B, Perkins GB, Wu H, Chadban S.   +5 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Botulinum Toxin (Dysport) to Prevent Radiation-Induced Dysfunction of Salivary Glands in Head and Neck Cancer. [PDF]

Cancer Rep (Hoboken)
Farhan F, Eyvaz-Zadeh I, Forghani S, Shahsavand A, Samiee R, Mansouri S, Abbasi M, Kazemian A, Aghili M, Jafari M, Karimi E, Esmati E, Jafari F.   +12 more
europepmc   +1 more source

Multidimensional toxicity of snake venom causes multi-organ damage and treatment challenges: a narrative review. [PDF]

Front Pharmacol
Tong D, Chen L, Xu J.
europepmc   +1 more source