Results 221 to 230 of about 987,804 (362)

The Cysteine-rich Secretory Protein Domain of Tpx-1 Is Related to Ion Channel Toxins and Regulates Ryanodine Receptor Ca2+ Signaling [PDF]

, 2005
Gerard M. Gibbs, M.J. Scanlon, James Swarbrick, Suzanne M. Curtis, Esther M. Gallant, Angela F. Dulhunty, Moira K. O’Bryan   +6 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Outbreak of equine botulism type C associated with consumption of baleage in Brazil. [PDF]

J Vet Diagn Invest
Souza LL, Lima AS, Martins AS, Silva TA, Borsanelli AC, Dutra IS, Pupin RC, Gomes DC, Lemos RA.   +8 more
europepmc   +1 more source

Regulation of Osteoblast Differentiation by Pasteurella Multocida Toxin (PMT): A Role for Rho GTPase in Bone Formation [PDF]

, 2004
Dympna Harmey, Gudrun Stenbeck, Catherine D. Nobes, Alistair J. Lax, Agamemnon E. Grigoriadis   +4 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Development of a direct PCR assay for detection of the diphtheria toxin gene [PDF]

, 1997
Hiroshi Nakao, T. Popovic
openalex   +1 more source

Case of a 35‐Year‐Old Man With Pain With Sneezing and Leg Weakness Causing Collapse

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This case details a 35‐year‐old man with no past medical history who presents with acute paraparesis and urinary retention in the setting of progressive paresthesias and weakness of his lower and upper extremities over several months. He was found to have longitudinally extensive transverse myelitis involving the cervical to mid‐thoracic cord ...
Joey Hsu, Karen Schoedel, Alan Plotzker, Leana Doherty   +3 more
wiley   +1 more source

Screening of Bacillus thuringiensis Isolates Recovered from Diverse Habitats in India for Crystal Toxin Genes Predicting Toxicity Against Three Insect Orders: Lepidoptera, Coleoptera, and Hemiptera [PDF]

Subhash Chandra Nangli B A, J Tharunkumar, S Pallavi, Akshay Bharat Ghodake, Sarvjeet Kaur   +4 more
openalex   +1 more source

Effects of piperacillin/tazobactam on Clostridium difficile growth and toxin production in a human gut model [PDF]

, 2005
Simon D. Baines, Jane Freeman, Mark H. Wilcox   +2 more
openalex   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source