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In vitro immunotoxicity of important mycotoxins detected in commercial dry dog and cat food in relation to internal exposure. [PDF]
Mycotoxin ResDänicke S +7 more
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Anesthesiology Clinics of North America, 2006
Exposures to toxins are prevalent, frequently complicate surgical emergencies, and impact critical care. A fundamental understanding of pathophysiologic principles and management strategies is essential for the anesthesiologist frequently responsible for the acute care of patients who have toxicologic exposures. Given their pervasiveness and ability to
John E, Sather, Hossam, Tantawy
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Exposures to toxins are prevalent, frequently complicate surgical emergencies, and impact critical care. A fundamental understanding of pathophysiologic principles and management strategies is essential for the anesthesiologist frequently responsible for the acute care of patients who have toxicologic exposures. Given their pervasiveness and ability to
John E, Sather, Hossam, Tantawy
openaire +2 more sources
Toxins: Bacterial and Marine Toxins
Clinics in Laboratory Medicine, 2006The term toxin refers in a specific way to a toxic substance of biologic origin; that is, a true toxin is a poison produced by a living organism. The purpose of this article is to review some of the most potentially dangerous toxins of concern today. Mechanisms of action, routes of exposure, diagnostic tools, and treatment recommendations are addressed.
Matthew, Salzman +2 more
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Trends in Microbiology, 2001
Researchers from Harvard Medical School have identified mutants of the anthrax toxin that could be used in the development of a therapeutic vaccine, as reported in Science. Rats injected with mutant protective antigen and a normally lethal dose of the anthrax toxin survived, suggesting that the mutant antigen could be useful as both a vaccine and an ...
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Researchers from Harvard Medical School have identified mutants of the anthrax toxin that could be used in the development of a therapeutic vaccine, as reported in Science. Rats injected with mutant protective antigen and a normally lethal dose of the anthrax toxin survived, suggesting that the mutant antigen could be useful as both a vaccine and an ...
openaire +1 more source
Hormone, lectin and toxin-toxin conjugates
1988In order to better understand the relative importance of the A and B chains of diphtheria toxin and ricin, chimeras or hybrid toxins have been constructed with diphtheria toxin subunits and ricin subunits coupled to a number of different binding moieties.
T N, Oeltmann, R G, Wiley
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Current Opinion in Structural Biology, 1995
Crystal structures of shiga and pertussis toxins have recently revealed a remarkable degree of structural homology among the members of the AB5 class of bacterial toxins. Other structures have provided a detailed view of the molecular basis of receptor binding specificity of cholera toxin, and of the heat-labile enterotoxin of Escherichia coli.
E A, Merritt, W G, Hol
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Crystal structures of shiga and pertussis toxins have recently revealed a remarkable degree of structural homology among the members of the AB5 class of bacterial toxins. Other structures have provided a detailed view of the molecular basis of receptor binding specificity of cholera toxin, and of the heat-labile enterotoxin of Escherichia coli.
E A, Merritt, W G, Hol
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Epsilon toxin: a fascinating pore‐forming toxin
The FEBS Journal, 2011Epsilon toxin (ETX) is produced by strains of Clostridium perfringens classified as type B or type D. ETX belongs to the heptameric β‐pore‐forming toxins including aerolysin and Clostridium septicum alpha toxin, which are characterized by the formation of a pore through the plasma membrane of eukaryotic cells consisting in a β‐barrel of 14 amphipatic β
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Clinical Reviews in Allergy, 1993
We have presented in some detail the more common clinical syndromes produced by the ingestion of natural seafood toxins, and touched on those that could be of interest to the international traveler and to the sport fisherman. For the practicing allergist, knowledge of this wide array of clinical syndromes of toxicity is of paramount importance for the ...
A M, Saavedra-Delgado, D D, Metcalfe
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We have presented in some detail the more common clinical syndromes produced by the ingestion of natural seafood toxins, and touched on those that could be of interest to the international traveler and to the sport fisherman. For the practicing allergist, knowledge of this wide array of clinical syndromes of toxicity is of paramount importance for the ...
A M, Saavedra-Delgado, D D, Metcalfe
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Cellular and Molecular Life Sciences (CMLS), 1999
Though its lethal effects were ascribed to an exotoxin almost half a century ago, the pathogenesis of anthrax has yet to be satisfactorily explained. Subsequent work has led to the molecular identification and enzymatic characterization of three proteins that constitute two anthrax toxins.
N S, Duesbery, G F, Vande Woude
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Though its lethal effects were ascribed to an exotoxin almost half a century ago, the pathogenesis of anthrax has yet to be satisfactorily explained. Subsequent work has led to the molecular identification and enzymatic characterization of three proteins that constitute two anthrax toxins.
N S, Duesbery, G F, Vande Woude
openaire +2 more sources