Results 161 to 170 of about 3,656,607 (353)

A seroprevalence study indicates a high proportion of clinically undiagnosed MPXV infections in men who have sex with men in Berlin, Germany

BMC Infectious Diseases
Introduction During the mpox outbreak in 2022, the highest number of cases in Germany were registered in Berlin, almost all of them in men who have sex with men (MSM). However, the frequency of clinically undiagnosed infections is unknown.
Ulrich Marcus, Janine Michel, Nikolay Lunchenkov, Denis Beslic, Fridolin Treindl, Rebecca Surtees, Christoph Weber, Axel Baumgarten, Andreas Nitsche, Daniel Stern   +9 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Toxicity induced by Solanapyrone A in Chickpea shoots and its metabolism through Glutathione/Glutathione-S-Transferase system [PDF]

, 2013
Solanapyrone A and C were isolated from a Pakistani isolate of Ascochyta rabiei, Pk-1. Two experiments were conducted to investigate the phytotoxic effects of the most potent toxin, solanapyrone A on chickpea cultivars and its subsequent detoxification ...
Abdur Rauf, C., Haque, I., Naz, F., Nicklin, Jane, Qadir, G., Riaz, A.   +5 more
core  

Biological warfare, bioterrorism, biodefence and the biological and toxin weapons convention

Electronic Journal of Biotechnology, 1999
Biological warfare is the intentional use of micro-organisms, and toxins, generally of microbial, plant or animal origin to produce disease and death in humans, livestock and crops. The attraction of bioweapons in war, and for use in terroristic attacks is attributed to easy access to a wide range of disease-producing biological agents, to their low ...
openaire   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The US Statement at the Fifth Review Conference: Compounding the Error in Rejecting the Composite Protocol [PDF]

, 2002
Ye
Dando, Malcolm R., Pearson, Graham S., Sims, N.A.   +2 more
core  

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Machine learning-supported framework for the classification of mpox infection and MVA immunization from multiplexed serology data

Nature Communications
The 2022 global mpox outbreak highlighted the risk of zoonotic diseases establishing sustained transmission in human populations and underscored the need for accurate serological tools to monitor orthopoxvirus exposure. However, cross-reactive antibodies
Rebecca Surtees, Fridolin Treindl, Shakhnaz Akhmedova, Denis Beslic, Fatimanur Bayram, Akin Sesver, My Linh Nguyen, Thomas Rinner, Marica Grossegesse, Martin Skiba, Janine Michel, Nils Körber, Klaus Jansen, Uwe Koppe, Ulrich Marcus, Nicole Friedrich, Annette Mankertz, Katharina Ladewig, Hans Werner Mages, Brigitte G. Dorner, Andreas Nitsche, Daniel Stern   +21 more
doaj   +1 more source

Algal polyunsaturated fatty acids and effects on plankton ecology and other organisms [PDF]

, 2004
A review and discussion of the effects of algal polyunsaturated fatty acids (PUFAs) on phytoplankton and zooplankton ecology and their effects on other animal systems.
Ikawa, Miyoshi
core   +1 more source