Results 181 to 190 of about 2,559,591 (306)

Combined Exposure to Deoxynivalenol and Patulin Aggravates Liver Injury in Mice via Triggering Inflammation, Apoptosis, and Oxidative Stress. [PDF]

Toxins (Basel)
Zhao Q, Xu Z, Dai X, Zhang X, Li M, Chang J, Yin Q, Yang G, Liu C.   +8 more
europepmc   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Specific Binding Agents for the Molecular Recognition of Biotoxins: Recent Advances and Applications in Forensic Toxicology. [PDF]

Molecules
Li C, Wu W, Huang Q, Huang Y.
europepmc   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Uremic toxins promote renal fatty acid synthesis and fibrosis via activating aryl hydrocarbon receptor. [PDF]

Nat Commun
Xie H, Zhang Y, Lu L, Guo H, Sun X, Ning M, Xie X, Li L, Niu Y, Li J, Wang X, Wu L, Zhou L, Zhang W, Zhang Y, Xu C, Lu L, Yu C.   +17 more
europepmc   +1 more source

Pandoomain, a scalable pipeline for genomic and protein domain context analysis, reveals widespread PT-TG domain architectural diversity and novel polymorphic toxins. [PDF]

mSystems
Soto EB, Oliver AJ, de Moraes MH.
europepmc   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

Integrated Venom Gland Transcriptomic and Venom Proteomic Analyses of the Digger Wasp <i>Cerceris japonica</i>. [PDF]

Toxins (Basel)
Kazuma K, Tani N, Konno K, Kawaguchi M, Inagaki H.   +4 more
europepmc   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

High-Throughput Characterization of Human Fibroblast Responses to a Panel of <i>Staphylococcus aureus</i> Antigen Proteins Using Olink Proteomics. [PDF]

Open Forum Infect Dis
Dalloul RSD, Sohail MU, Chennakkandathil S, Sawarth H, Al-Noubi M, Choi S, Schmidt F.   +6 more
europepmc   +1 more source