Results 61 to 70 of about 3,656,607 (353)

Estimation of the Minimum Number of Replication Origins Per Chromosome in any Organism

Bio-Protocol, 2020
Eukaryote nuclear genomes predominantly replicate through multiple replication origins. The number of replication origins activated per chromosome during the S-phase duration may vary according to many factors, but the predominant one is replication ...
Marcelo da Silva
doaj   +1 more source

Environmental risk assessment of genetically modified plants - concepts and controversies [PDF]

, 2011
Background and purpose: In Europe, the EU Directive 2001/18/EC lays out the main provisions of environmental risk assessment (ERA) of genetically modified (GM) organisms that are interpreted very differently by different stakeholders. The purpose of this
A Hilbeck, A Hilbeck, A Hilbeck, A Hilbeck, A Hilbeck, A Hilbeck, A Lang, A Raps, A Raybould, A Raybould, AL Cerdeira, ANE Birch, B Lutz, C Hawes, C Zwahlen, C Zwahlen, CB Blackwood, CBD, Council of the European Union, D Saxena, DA Andow, DA Andow, DA Andow, DJ Baird, EC, EC, EFSA, EJ Rosi-Marshall, Environmental Protection Agency (EPA), EP Millstone, EPA Environmental Protection Agency OPPTS 7501P, EurActive, FAO/WHO, J Romeis, J Romeis, J Romeis, J Scheirs, JD Harwood, JD Harwood, KC Nelson, KC Nelson, KR Hayes, KR Hayes, LB Obrist, M Dolezel, M Douville, M Garcia-Alonso, M Mendelsohn, MC Arregui, MR Berenbaum, National Research Council (NRC), OECD, OECD (Organisation for Economic Cooperation and Development), PM Chapman, Royal Society of Canada, T Bøhn, VE Forbes, W Freese   +57 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

N-Glycosylation Profile of Abrin Certified EU Reference Material

Toxins
Abrin is a highly toxic plant protein encompassing four isoforms, abrin-a, -b, -c and -d. An abrin reference material was isolated from Abrus precatorius and certified (EURM-113) by the EuroBioTox consortium.
Roland Josuran, Andreas Wenger, Sylvia Worbs, Bettina Kampa, Andreas Rummel, Brigitte G. Dorner, Sabina Gerber   +6 more
doaj   +1 more source

Structural and Functional Diversity of Animal Toxins Interacting With GPCRs

Frontiers in Molecular Biosciences, 2022
Peptide toxins from venoms have undergone a long evolutionary process allowing host defense or prey capture and making them highly selective and potent for their target.
Anne-Cécile Van Baelen, Philippe Robin, Pascal Kessler, Arhamatoulaye Maïga, Arhamatoulaye Maïga, Nicolas Gilles, Denis Servent   +6 more
doaj   +1 more source

Article X: Specific Measures to Achieve Implementation [PDF]

, 1998
Ye
Pearson, Graham S.
core  

Biologically Active Peptides in Physalia Toxin.

Experimental Biology and Medicine, 1961
Summary and conclusionsThe crude toxin of Physalia nematocysts withstands lyophilization without significant loss of toxicity. Physalia toxin may be separated into component peptides by one-dimensional chromatography in 80% aqueous n-propanol. Each of the resultant peptides retains considerable toxicity for the fiddler crab, Uca pugilator.
C E, LANE, B W, COURSEN, K, HINES
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

The BTWC Protocol: Proposed Complete Text for an Integrated Regime [PDF]

, 2000
Ye
Dando, Malcolm R., Kenyon, I.R., Pearson, Graham S., Sims, N.A.   +3 more
core  

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source