Results 221 to 230 of about 919,409 (398)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

<i>Megalomyrmex milenae</i> Transcriptome Reveals a Complex Venom Cocktail. [PDF]

open access: yesToxins (Basel)
Sozanski KS   +4 more
europepmc   +1 more source

DIPHTHERIA TOXIN

open access: yesJournal of Biological Chemistry, 1937
openaire   +2 more sources

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Review on uremic toxins: classification, concentration, and interindividual variability.

open access: yesKidney International, 2003
R. Vanholder   +21 more
semanticscholar   +1 more source

BordetellaDermonecrotic Toxin Is a Neurotropic Virulence Factor That Uses CaV3.1 as the Cell Surface Receptor

open access: gold, 2020
Shihono Teruya   +13 more
openalex   +1 more source

Duodenitis-Proximal Jejunitis in Horses After Experimental Administration of Clostridium difficile Toxins [PDF]

open access: gold, 2016
Luis G. Arroyo   +5 more
openalex   +1 more source

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