Results 81 to 90 of about 919,409 (398)

From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery

Frontiers in Pharmacology, 2020
Animal poisons and venoms are comprised of different classes of molecules displaying wide-ranging pharmacological activities. This review aims to provide an in-depth view of toxin-based compounds from terrestrial and marine organisms used as diagnostic ...
Karla de Castro Figueiredo Bordon, Camila Takeno Cologna, Elisa Corrêa Fornari-Baldo, Ernesto Lopes Pinheiro-Júnior, Felipe Augusto Cerni, Fernanda Gobbi Amorim, Fernando Antonio Pino Anjolette, Francielle Almeida Cordeiro, Gisele Adriano Wiezel, Iara Aimê Cardoso, Isabela Gobbo Ferreira, Isadora Sousa de Oliveira, Johara Boldrini-França, Manuela Berto Pucca, Mateus Amaral Baldo, Eliane Candiani Arantes   +15 more
doaj   +1 more source

Alternaria Toxins: Potential Virulence Factors and Genes Related to Pathogenesis

Frontiers in Microbiology, 2017
Alternaria is an important fungus to study due to their different life style from saprophytes to endophytes and a very successful fungal pathogen that causes diseases to a number of economically important crops.
M. Meena, Sanjay Gupta, P. Swapnil, Andleeb Zehra, M. Dubey, R. Upadhyay   +5 more
semanticscholar   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

The Effect of Purified Opharin Isolated from the Venom of King Cobra (Ophiophagus hannah) in Modulating Macrophage Inflammatory Responses and Vascular Integrity

Toxins
King cobra (Ophiophagus hannah) venom comprises a diverse array of proteins and peptides. However, the roles and properties of these individual components are still not fully understood.
Tuchakorn Lertwanakarn, Armando Reyes, Emelyn Salazar, Martha Barrientos, Elda E. Sanchez, Montamas Suntravat   +5 more
doaj   +1 more source

m1-toxin

Life Sciences, 1993
The venom of the Eastern green mamba from Africa, Dendroaspis angusticeps, contains a number of toxins which block the binding of 3H-antagonists to genetically-defined m1 and m4 muscarinic acetylcholine receptors. Most of the anti-muscarinic activity of the venom is due to the presence of a newly-isolated toxin, "m1-toxin", which has 64 amino acids and
L T, Potter, H, Hanchett-Valentine, J S, Liang, S I, Max, S L, Purkerson, H A, Silberberg, W L, Strauss   +6 more
openaire   +2 more sources

Marine toxins [PDF]

British Medical Bulletin, 2000
Seafood products are important both nutritionally and economically. Within Europe, some 12 billion Pounds of fishery products are consumed annually and an enormous variety of species are available. Although seafood is rarely implicated in food poisoning, compared to other food sources, it does provide some specific human health hazards unique to this ...
K, Whittle, S, Gallacher
openaire   +2 more sources

Sea Anemones: Quiet Achievers in the Field of Peptide Toxins

Toxins, 2018
Sea anemones have been understudied as a source of peptide and protein toxins, with relatively few examined as a source of new pharmacological tools or therapeutic leads. This is surprising given the success of some anemone peptides that have been tested,
P. Prentis, A. Pavasovic, R. Norton
semanticscholar   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Snake venom cysteine-rich secretory protein from Mojave rattlesnake venom (Css-CRiSP) induces acute inflammatory responses on different experimental models

Toxicon: X
Snake venoms contain various molecules known for activating innate immunity and causing local effects associated with increased vascular permeability, such as vascular leakage and edema, common symptoms seen in snakebite envenomings. We have demonstrated
Emelyn Salazar, Abcde Cirilo, Armando Reyes, Martha Barrientos, Jacob Galan, Elda E. Sánchez, Montamas Suntravat   +6 more
doaj   +1 more source

Studies on Resistance to Vegetative (Vip3A) and Crystal (Cry1A) Insecticidal Toxins of Bacillus thuringiensis in Heliothis virescens (Fabricius) [PDF]

, 2009
Bacillus thuringiensis (Bt) toxins expressed in commercial transgenic crop varieties are all δ-endotoxins (Cry toxins) but the identification of novel vegetative insecticidal proteins (Vip toxins) has extended the range of insecticidal proteins derived
Pickett, Brian R, Pickett, Brian R
core   +1 more source