Results 101 to 110 of about 144,290 (309)

Sekuen Gen Surface Antigen-1 dan Bradizoit Antigen-1 Takizoit Toxoplasma gondii sebagai Kandidat Pemindai DNA (SAG1 AND BAG1 GENE SEQUENCES ANALYSIS OF TOXOPLASMA GONDII TACHYZOITE AS PROBE CANDIDATE)

Jurnal Veteriner, 2013
Sag1 and bag1 is a gene specific-stage for Toxoplasma gondii tachyzoite and bradyzoite. The purposeof this study was analyze the sequences of sag1 and bag1 tachyzoite genes of local of Toxoplasma gondiiisolate as deoxyribonucleic acid probe candidate ...
Ida Ayu Pasti Apsari, Wayan Tunas Artama, Sumartono ., I Made Damriyasa   +3 more
doaj  

Analysis of the Correlation Between Toxoplasma gondii Seropositivity and Alzheimer’s Disease

Pathogens
Alzheimer’s disease (AD) is a multifactorial brain disorder and infectious diseases are considered as one of the predisposing factors for AD. Toxoplasma gondii, an obligate intracellular parasitic protozoan, is suspected of being associated with AD ...
Jianjun Wang, Ping Lin, Dan Li, Biyu Yang, Jiaqi Wang, Meng Feng, Xunjia Cheng   +6 more
doaj   +1 more source

Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, China

International Journal of Infectious Diseases, 2015
Objective: Infection by the protozoan parasite Toxoplasma gondii is generally prevalent in animals and humans worldwide. However, little is known about T. gondii infection among children in China.
Qing-Feng Meng, Hai-Long You, Na Zhou, Wei Dong, Wei-Lin Wang, Wei-Li Wang, Wei Cong   +6 more
doaj   +1 more source

Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondii

mBio, 2017
Cyclic GMP (cGMP)-dependent protein kinase (protein kinase G [PKG]) is essential for microneme secretion, motility, invasion, and egress in apicomplexan parasites, However, the separate roles of two isoforms of the kinase that are expressed by some ...
Kevin M. Brown, Shaojun Long, L. Sibley
semanticscholar   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Computational Motility Tracking of Calcium Dynamics in Toxoplasma gondii [PDF]

arXiv, 2017
Toxoplasma gondii is the causative agent responsible for toxoplasmosis and serves as one of the most common parasites in the world. For a successful lytic cycle, T. gondii must traverse biological barriers in order to invade host cells, and as such, motility is critical for its virulence. Calcium signaling, governed by fluctuations in cytosolic calcium
arxiv  

Advances in the Study of Pluripotent Stem Cells in Livestock

Cell Proliferation, EarlyView.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou, Chen Gao, Wenxuan Zhao, Xinhua Wei, Dawei Yu, Huiying Zou, Weihua Du   +6 more
wiley   +1 more source

Selection at a single locus leads to widespread expansion of toxoplasma gondii lineages that are virulent in mice [PDF]

, 2009
The determinants of virulence are rarely defined for eukaryotic parasites such as T. gondii, a widespread parasite of mammals that also infects humans, sometimes with serious consequences.
A Barragan, A Fazaeli, A Giulietti, A Khan, A Khan, A Khan, A Khan, AL Hughes, Asis Khan, B Carme, B Gajria, B Korber, Benjamin M. Rosenthal, C Jung, C Su, D Ajzenberg, D Jacobs, DG Higgins, DG Mordue, DK Howe, DK Howe, DL Swofford, H El Hajj, H El Hajj, HJ Bandelt, I Fuentes, James W. Ajioka, JC Boothroyd, JK Frenkel, JP Boyle, JP Boyle, JP Dubey, JP Dubey, JP Dubey, JPJ Saeij, JPJ Saeij, JR Radke, JT Kong, KJH Robson, L. David Sibley, LD Sibley, LM Weiss, M Messina, M Nei, ME Grigg, MJ Mackinnon, ML Dardé, ML Dardé, O Liesenfeld, P Bastin, PJ Bradley, PM Robben, S Kumar, S Taylor, SA Frank, SL Kosakovsky-Pond, SM Rich, Sonya Taylor, T Lehmann, T Ota, Takashi Gojobori, Y Suzuki   +61 more
core   +4 more sources

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Unsupervised Discovery of Toxoplasma gondii Motility Phenotypes [PDF]

arXiv, 2018
Toxoplasma gondii is a parasitic protozoan that causes dis- seminated toxoplasmosis, a disease that afflicts roughly a third of the worlds population. Its virulence is predicated on its motility and ability to enter and exit nucleated cells; therefore, studies elucidating its mechanism of motility and in particular, its motility patterns in the context
arxiv