Results 71 to 80 of about 159,524 (313)

Protection induced by virus-like particles containing Toxoplasma gondii microneme protein 8 against highly virulent RH strain of Toxoplasma gondii infection. [PDF]

open access: yesPLoS ONE, 2017
Toxoplasma gondii (T. gondii) microneme protein 8 (MIC8) represents a novel, functional distinct invasion factor. In this study, we generated virus-like particles (VLPs) targeting Toxoplasma gondii MIC8 for the first time, and investigated the protection
Su-Hwa Lee   +5 more
doaj   +1 more source

Toxoplasma gondii: Biological Parameters of the Connection to Schizophrenia

open access: yesSchizophrenia bulletin, 2018
It is increasingly evident that the brain is not truly an immune privileged site and that cells of the central nervous system are sensitive to the inflammation generated when the brain is fighting off infection.
Jianchun Xiao   +6 more
semanticscholar   +1 more source

Toxoplasma gondii in the Food Supply [PDF]

open access: yesPathogens, 2017
Toxoplasmosis is caused by infection with the protozoan parasite Toxoplasma gondii. Infections are usually either asymptomatic or develop mild symptoms that are self-limited, but infections in immunosuppressed persons can be severe. Infections in pregnant women can cause serious health problems in the child such as mental retardation and blindness ...
Hussain, Malik A. (R20588)   +3 more
openaire   +3 more sources

Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy

open access: yesAnnals of Neurology, EarlyView.
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal   +7 more
wiley   +1 more source

Clinical, parasitological and obstetric observations in pregnant bitches with experimental toxoplasmosis [PDF]

open access: yesCiência Rural, 2001
Eight pregnant mixed breed bitches, serologically negative for Toxoplasma gondii, were divided into three groups. Group I : bitches 01 and 02 (1.0 x 10(7) tachyzoites of Toxoplasma gondii, subcutaneous route); Group II: bitches 03, 04 and 05 (1.5 x 10(4)
Katia Denise Saraiva Bresciani   +4 more
doaj   +1 more source

Characterization of exosomes derived from Toxoplasma gondii and their functions in modulating immune responses

open access: yesInternational Journal of Nanomedicine, 2018
Introduction Exosomes are nanograde membrane-bound vesicles secreted from most cell types through the fusion of multivesicular bodies with plasma membranes.
Yawen Li   +9 more
semanticscholar   +1 more source

Detection of high levels of congenital transmission of toxoplasma gondii in natural urban populations of mus domesticus [PDF]

open access: yes, 2004
The relative importance of different transmission routes of Toxoplasma gondii has been a matter for debate. This ubiquitous parasite is generally thought to be transmitted by infective oocysts excreted by the definitive host, the cat.
Hide, G   +6 more
core   +1 more source

The RNA of Toxoplasma gondii

open access: yesExperimental Biology and Medicine, 1970
SummaryIsolation and characterization of toxoplasma RNA revealed a ribosomal species which could be easily differentiated from mammalian host cell RNA. A species of transfer RNA also appeared to differ from that of the host cell. Extracellular toxoplasma were capable of incorporating 3H-uridine into the major components of their RNA.
William S. Robinson   +3 more
openaire   +3 more sources

Mechanism and role of regulated cell death in tumor immunity and immunotherapy

open access: yesCancer Communications, EarlyView.
Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu   +4 more
wiley   +1 more source

Toxoplasma gondii Infection in Immunocompromised Patients: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Microbiology, 2017
Toxoplasma gondii has been suggested as an important opportunistic pathogen in immunocompromised patients. We conducted a global meta-analysis to assess the prevalence and odds ratios (ORs) of T.
Zedong Wang   +9 more
semanticscholar   +1 more source

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