Label-free tissue proteomics can classify oral squamous cell carcinoma from healthy tissue in a stage-specific manner [PDF]
, 2018 Objectives: No prognostic or predictive biomarkers for oral squamous cell carcinoma (OSCC) exist. We aimed to discover novel proteins, altered in OSCC, to be further investigated as potential biomarkers, and to improve understanding about pathways ...
Dickinson, Amy +7 more
core +1 more source
Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q [PDF]
, 2017 Endothelial Protein C Receptor (EPCR) is a Major Histocompatibility Complex homologue, with established roles downregulating coagulation and in endothelial protection.
Beggs, Andrew +6 more
core +1 more source
TPD52和TPD52L2在胃癌中异常表达的临床病理特征分析和相关基因共表达意义研究 附视频
Zhongguo shiyan zhenduanxue目的 应用生物信息学的方法探讨肿瘤蛋白D52(tumor protein D52,TPD52)和肿瘤蛋白D52样2(tumor protein D52-like 2,TPD52L2)在胃癌中异常表达的临床病理特征，并分析相关基因共表达的意义。方法 基于癌症基因组图谱(The Cancer Genome AHas, TCGA)获取数据，利用R语言软件包比较TPD52和TPD52L2在胃癌组织和癌旁组织中的差异表达与临床病理特征的相关性，并探索与免疫细胞浸润水平的情况，Kaplan ...
doaj +2 more sources
Verifica di potenziali biomarcatori in pazienti con disturbo bipolare [PDF]
, 2015 Questo lavoro di tesi nasce da uno studio comparativo condotto e pubblicato nel 2014 che ha visto l’utilizzo dell’elettroforesi bidimensionale, accoppiata a spettrofotometria di massa, per caratterizzare e confrontare il contenuto proteico di linfociti ...
PELOSI, ALICE
core
DDoS: A Graph Neural Network based Drug Synergy Prediction Algorithm
, 2022 Background: Drug synergy occurs when the combined effect of two drugs is greater than the sum of the individual drugs' effect. While cell line data measuring the effect of single drugs are readily available, there is relatively less comparable data on ...
Allam, Ahmed +5 more
core
Analyzing Cat Blood Biomarkers Associated with Aging [PDF]
There is a gap in research focused on the aging process of the feline species. To this end we were dedicated to address this knowledge gap and its relationship to the impact of aging cats and the role of oxidative stress.
Marquez, Mariela Avalos
core
Altered Functional Protein Networks in the Prefrontal Cortex and Amygdala of Victims of Suicide [PDF]
, 2012 Czurkó, András +10 more
core +1 more source
Understanding the subcellular regulation of the NLRP3 inflammasome and IL-1a [PDF]
, 2023 Wellens, Rose
core
Identification of prognostic immune cells and potential immune-related markers in hepatocellular carcinoma. [PDF]
Transl Cancer Res, 2022 Mai J +5 more
europepmc +1 more source
Dual oncogenic roles of TPD52 and TPD52L2 in gastric cancer progression via PI3K/AKT activation and immunosuppressive microenvironment remodeling. [PDF]
Brief Funct GenomicsLi H +9 more
europepmc +1 more source