Results 91 to 100 of about 69,255 (308)

TPM-with-cluster_updated 5825.csv

The carotid body (CB) chemoreceptors mediate rapid cardiorespiratory responses to hypoxia, which maintain systemic oxygen homeostasis, but CB dysfunction is also implicated in pathologies including hypertension, heart failure and sudden infant death.CB ...
Emma Hodson (7561316)
core   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Security properties analysis in a TPM-based protocol

, 2014
Security protocols are designed in order to provide security properties (goals). They achieve their goals using cryptographic primitives such as key agreement or hash functions.
Suriadi, S, Foo, E, Seifi, Y, Boyd, C
core   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

Effect of Tooth Profile Modification on Dynamic Tooth Load of Planetary Gear Train

Shock and Vibration, 2019
This paper aims at investigating the effects of tooth profile modification (TPM) on the dynamic response of planetary gear train (PGT). A numerical model is carried out to calculate two major excitation sources of PGT, time-varying mesh stiffness (TVMS),
Jiaming Zhou, Fengyan Yi, Xiangyang Xu, Junbin Lai, Yanfang Liu, Peng Dong   +5 more
doaj   +1 more source

TPM structures.

, 2013
TPM structures.
Lucas Fonseca Rodrigues (288733), Ana Rabello (112015), Benjamin Lefkove (288744), Lucas Antônio Miranda Ferreira (288749), Jack Arbiser (230839), Eliane Teixeira (288737), Renata Celi Carvalho de Souza Pietra (288729), Levi Fried (288741), Ana Paula Fernandes (4220)   +8 more
core   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

A manutenção de condomínios em edifícios, tpm, terceirização e o jit/tqc.

Revista Tecnologia, 2009
A tendência atual é para se adotar o modo de vida e trabalho em condomínios. Cresce também a necessidade de uma real e efetiva manutenção, porque os consumidores desejam baixos custos e qualidade.
José Emído Alexandrino Bezerra, Dálvio Ferrari Tubino   +1 more
doaj  

TPM rendszer bevezetése Mazak QT kompakt típusú háromtengelyes esztergagépen

A szakdolgozatom célja az volt, hogy kidolgozzak egy teljeskörű hatékony karbantartási (total productive maintenance - TPM) rendszert és annak bevezetését a Mazak QTC 200 MS L esztergagépre.
Nyeste, Márk Norbert
core