Results 71 to 80 of about 69,255 (308)

Gestão de estoque de materiais de baixíssimo giro considerando processos críticos para a organização [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Civil, Florianópolis, 2009Este trabalho tem como objetivo analisar e apresentar quais são os impactos para as organizações, caso ...
Costa, Jener de Castro
core  

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

open access: yesAdvanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang   +11 more
wiley   +1 more source

Topiramate-induced hyperammonemic encephalopathy in a patient with mental retardation: A case report and review of the literature

open access: yesEpilepsy and Behavior Case Reports, 2015
Hyperammonemia is an uncommon side effect of topiramate (TPM) that has only been reported when it is used as an adjunct to valproate. We report a patient with mental retardation who developed reversible encephalopathy from TPM.
Sahawat Tantikittichaikul   +3 more
doaj   +1 more source

Manutenção produtiva total na adaptação estratégica: um estudo na Eletronorte de 1996 a 2001 [PDF]

open access: yes, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.A dissertação descreve e analisa o processo de adaptação estratégica da Eletronorte, no período 1996 a 2001 ...
Sena, Robésio Maciel de
core  

Total Tpm protein levels in the Tpm-overexpressing clones.

open access: yes, 2015
The total Tpm protein expression levels were determined in each Tpm-overexpressing clone. The expression of each Tpm isoform, evaluated by western blotting, was determined with the use of Tpm recombinant proteins and expressed as μg of Tpm per μg of ...
Hong Cheng (112057)   +11 more
core   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

Examination of the TPM initialization at Teva Pharmaceuticals Zrt. in Debrecen

open access: yes, 2016
Diplomadolgozatomban bemutattam a lean szemléletű TPM rendszer bevezethetőségének vizsgálatát. A minőséget azért ragadtam meg, mint fontos elemét a dolgozatomnak, mert az végigkíséri és javítja az ellátási láncunk értékteremtő lépéseit, továbbá a lean ...
Diószegi, Ferenc
core  

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

open access: yesAdvanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma   +11 more
wiley   +1 more source

Topiramate ameliorates abdominal aorta cross-clamping induced liver injury in rats

open access: yesThe Saudi Journal of Gastroenterology, 2014
Background and Aim : Ischemia/reperfusion (I/R) injury in the liver occurs after a prolonged period of ischemia followed by restoration of hepatic blood perfusion.
Erkan Cure   +8 more
doaj   +1 more source

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