Results 41 to 50 of about 16,305 (230)

The Predictive Value of tPSA, fPSA, fPSA/tPSA Combined with Ultrasound Parameters in Postoperative Gleason Grading of Prostate Cancer

Annali Italiani di Chirurgia
AIM: Prostate cancer (PCa) is a common malignant tumor in men. This study aimed to explore the predictive value of serum biomarkers combined with ultrasound parameters for postoperative Gleason grading in PCa. METHODS: This study included 65 PCa patients who underwent transurethral resection of the prostate in our hospital from January 2021 to December
Lianjuan, Liu, Fengyun, Wu, Xiaoyan, Ma, Weiling, Wang, Min, Zhang, Yanzhuo, Sun   +5 more
openaire   +2 more sources

Digital rectal examination (DRE) does not influence total serum levels of prostate specific antigen (tPSA), in individuals without prostate pathology

International Brazilian Journal of Urology, 2003
OBJECTIVE: To evaluate if the digital rectal examination (DRE) performed before determination of total serum prostate specific antigen (tPSA) influences the levels of this protein.
Maria de F. Figueirêdo, Galeno T. Lopes, Talapala G. Naidu   +2 more
doaj   +1 more source

Utjecaj supstituenata na NMR značajke temeljnog bicikličkog prstenastog sustava fluorokinolonskih antibiotika, odnos između NMR kemijskih pomaka, molekulskih opisivača i parametara sličnosti s lijekovima [PDF]

, 2010
In the present study, the NMR spectroscopic features of trovafloxacin (TVA) mesylate, pefloxacin (PFX) mesylate dihydrate and ciprofloxacin (CIP) hydrochloride monohydrate were studied in DMSO-d6 solution with the aim of investigating the effects of ...
MILENA JADRIJEVIĆ-MLADAR TAKAČ
core   +3 more sources

Generative AI‐Driven Accelerated Discovery of Passivation Molecules for Perovskite Solar Cells

Advanced Science, EarlyView.
A generative artificial intelligence (AI) framework combining a discriminative machine learning model (SMILES‐X) and a generative language model (GPT‐2) autonomously discovers new molecular passivators for perovskite solar cells (PSCs). Through an iterative design loop, over 100 000 candidates are generated and screened, and randomly selected molecules
Adroit T. N. Fajar, Guillaume Lambard, Jessie Manopo, Ruili Guo, Kevin Septioga, Rizfi F. Pari, Toshinori Matsushima, Zhanglin Guo   +7 more
wiley   +1 more source

EFFECTS OF CHRONIC RENAL FAILURE AND HEMODIALYSIS ON SERUM PSA, FREE PSA, FREE/TOTAL PSA RATIOS

Urology Research and Practice, 2019
Little is known of the impact of hemodialysis on serum total (tPSA) and free PSA (fPSA) levels. We prospectively studied the impact of hemodialysis with low-flux membranes on serum tPSA, fPSA and free/total PSA (f/tPSA) ratios.
G. Özer, B. Koçak, M. Altınel, Ş.A. Altan, F. Gönenç   +4 more
doaj   +2 more sources

Free Prostate-Specific Antigen Provides More Precise Data on Benign Prostate Volume Than Total Prostate-Specific Antigen in Korean Population [PDF]

International Neurourology Journal, 2013
Purpose: To investigate the efficacy of total prostate-specific antigen (tPSA) and free prostate-specific antigen (fPSA) for the estimation of prostate volume (PV) in pathologically-proven benign prostatic hyperplasia (BPH) patients.
Hoon Choi, Jae Young Park, Ji Sung Shim, Jae Heon Kim, Jae Hyun Bae   +4 more
doaj   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

Advanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv, Qianyang Wu, Jian Liu, Binlu Yang, Yuanhao Li, Junlin Xu, Yajie Meng, Leyi Wei, Zilong Zhang, Quan Zou, Xiulai Li, Feifei Cui   +11 more
wiley   +1 more source

Preventing Unnecessary Invasive Cancer-Diagnostic Tests: Changing the Cut-off Points [PDF]

Iranian Journal of Public Health, 2012
Background: To determine a cut-off point of tPSA and PSAD to prevent unnecessary invasive cancer-diagnosing tests in the community. Methods: This study was performed on 688 consecutive patients referred to our center due to prostatism, suspicious lesions
G Pourmand, R Ramezani, B Sabahgoulian, F Nadali, AR Mehrsai, MR Nikoobakht, F Allameh, SH Hossieni, A Seraji, M Rezai, F Haidari, S Dehghani, R Razmandeh, B Pourmand   +13 more
doaj   +1 more source

Artificial neural network (ANN) velocity better identifies benign prostatic hyperplasia but not prostate cancer compared with PSA velocity [PDF]

, 2008
Background To validate an artificial neural network (ANN) based on the combination of PSA velocity (PSAV) with a %free PSA-based ANN to enhance the discrimination between prostate cancer (PCa) and benign prostate hyperplasia (BPH).
Carsten Stephan, Nicola Büker, Henning Cammann, Hellmuth-Alexander Meyer, Michael Lein, Klaus Jung   +5 more
core   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source