Results 51 to 60 of about 2,852 (191)

Prevalence and predictors of osteoporosis/bmd below expected range for age in pheochromocytoma/paraganglioma and BMD, TBS change post-operatively: A prospective cohort study

Indian Journal of Endocrinology and Metabolism, 2023
Context: Pheochromocytomas/paragangliomas (PPGLs) have recently been shown to be associated with lower bone mineral density (BMD) and trabecular bone score as compared to healthy controls suggesting low bone mineral concentration and disrupted bone ...
Saurav Khatiwada, Shipra Agarwal, Devasenathipathy Kandasamy, Rajeev Kumar, Viveka P Jyotsna, Nikhil Tandon   +5 more
doaj   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

Advanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh, Hosni Cherif, Matthew Mannarino, Juiena Sagir, Magali Millecamps, Jean A. Ouellet, Laura S. Stone, Lisbet Haglund   +7 more
wiley   +1 more source

The Correlation between Trabecular Bone Score and Lumbar Spine Bone Mineral Density in Patients with Normal and High Body Mass Index [PDF]

Iranian Journal of Medical Sciences, 2019
Background: Trabecular bone score (TBS) measures the underlying quality of bone texture using dual-energy X-ray absorptiometry (DXA) images. The present study aimed to investigate the correlation between lumbar spine bone mineral density (BMD) and TBS ...
Alireza Rajaei, Ali Amiri, Faraneh Farsad, Pooneh Dehghan   +3 more
doaj   +1 more source

Therapy With Intravenous Methylprednisolone Pulses Is Associated With Loss of Bone Microarchitecture in Trabecular Bone Score -Assessment Among Patients With Moderate-to-Severe Graves’ Orbitopathy: A Pilot Study

Frontiers in Endocrinology, 2022
BackgroundTherapy with intravenous glucocorticoids (GCs) is associated with various side effects, however, the impact on bone remains elusive. Trabecular bone score (TBS) is a diagnostic tool providing information on bone microarchitecture based on ...
Joanna Rymuza, Katarzyna Pelewicz, Jerzy Przedlacki, Piotr Miśkiewicz   +3 more
doaj   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Reference Ranges for Trabecular Bone Score in Australian Men and Women: A Cross‐Sectional Study

JBMR Plus, 2019
Trabecular bone score (TBS) is a novel method for indirectly assessing trabecular microarchitecture at the lumbar spine, providing information complementary to areal BMD.
Kara B Anderson, Kara L Holloway‐Kew, Didier Hans, Mark A Kotowicz, Natalie K Hyde, Julie A Pasco   +5 more
doaj   +1 more source

Assessment of bone quality with trabecular bone score in patients with inflammatory bowel disease

Scientific Reports, 2021
Inflammatory bowel disease (IBD) patients have a significant risk of developing bone loss. The trabecular bone score (TBS) is a relatively new parameter used to provide information on bone quality.
Iulia Soare, Anca Sirbu, Sorina Martin, Mircea Diculescu, Bogdan Mateescu, Cristian Tieranu, Simona Fica   +6 more
doaj   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Trabecular bone score in healthy ageing [PDF]

, 2014
The main aim of this work was to report on trabecular bone score (TBS) by dual-energy X-ray absorptiometry (DXA) of healthy Italian subjects to be used as a reference standard for future study in clinical and research settings.
Ponti, F., Diano, Danila, Amadori, M, Ponti, Federico, Bazzocchi, A, Guglielmi, Giuseppe, Albisinni, U, Diano, D., Alberto Bazzocchi, Battista, G, Albisinni, U., Amadori, Michele, Diano, D, Ponti, F, Battista, Giuseppe, Ugo Albisinni, Federico Ponti, Giuseppe Guglielmi, Bazzocchi, A., Albisinni, Ugo, Bazzocchi, Alberto, Michele Amadori, Danila Diano, Guglielmi, G., Amadori, M., Giuseppe Battista   +25 more
core   +1 more source

Trabecular Bone Score and Bone Mineral Density in Men with Vertebral Fractures

Bolʹ, Sustavy, Pozvonočnik, 2015
Traditionally bone mineral density (BMD) has been considered a major determinant of bone strength. However, it is shown that the bone strength and fracture risk depend on several parameters: macrogeometry of cortical bone, BMD, trabecular bone ...
V.V. Povoroznyk, A.S. Musiienko, N.I. Dzerovych   +2 more
doaj   +1 more source