Results 11 to 20 of about 13,663 (198)
Human Trabecular Meshwork Progenitors [PDF]
International Journal of Medical Sciences, 2019 Trabecular meshwork (TM) cells are a group of progenitors that have the ability to become adipocytes, chondrocytes and endothelial cells. Therefore, those adult corneal progenitors may be used as an effective therapy for trabecular meshwork diseases such as glaucoma, corneal endothelial dysfunctions such as blindness due to corneal endothelial ...
Zhu, Qin +5 more
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Pharmaceutics, 2021 In glaucoma therapy, nanoparticles (NPs) are a favorable tool for delivering drugs to the outflow tissues of the anterior chamber of the eye where disease development and progression take place.
Tobias Sonntag +5 more
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Tetramethylpyrazine (TMP), an Active Ingredient of Chinese Herb Medicine Chuanxiong, Attenuates the Degeneration of Trabecular Meshwork through SDF-1/CXCR4 Axis. [PDF]
PLoS ONE, 2015 A traditional Chinese medicine, Tetramethylpyrazine (TMP), has been prescribed as a complementary treatment for glaucoma to improve patient prognosis. However, the pharmacological mechanism of action of TMP is poorly understood.
Na Yu +12 more
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Trabecular meshwork stiffness in glaucoma [PDF]
Experimental Eye Research, 2017 Alterations in stiffness of the trabecular meshwork (TM) may play an important role in primary open-angle glaucoma (POAG), the second leading cause of blindness. Specifically, certain data suggest an association between elevated intraocular pressure (IOP) and increased TM stiffness; however, the underlying link between TM stiffness and IOP remains ...
Ke, Wang +3 more
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Biomaterials and Biosystems, 2021 Glaucoma is the second leading cause of irreversible blindness worldwide. Glaucoma is a progressive optic neuropathy in which permanent loss of peripheral vision results from neurodegeneration in the optic nerve head.
Devon J. Crouch +4 more
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Oxidative damage and autophagy in the human trabecular meshwork as related with ageing.
PLoS ONE, 2014 Autophagy is an intracellular lysosomal degradation process induced under stress conditions. Autophagy also plays a major role in ocular patho-physiology. Molecular aging does occur in the trabecular meshwork, the main regulator of aqueous humor outflow,
Alessandra Pulliero +5 more
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Lysyl Oxidases in the Trabecular Meshwork [PDF]
Journal of Glaucoma, 2014 The mechanical properties of the extracellular matrix (ECM) play an important role in maintaining cellular function and overall tissue homeostasis. Emerging evidence suggests that biomechanical modifications of the ECM may be initiators and/or drivers of disease, exemplified by increased tissue stiffness.
Robert J, Wordinger, Abbot F, Clark
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Journal of Agromedicine and Medical Sciences (AMS), 2017 In primary open angle glaucoma, decrease of hyaluronic acid level is related to extracellular matrix deposition of trabecular meshwork. Extracellular matrix deposition will increase humor aqueous outflow resistance which in turn increase the intraocular ...
Cicih Komariah +2 more
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Association between Myopia, Biometry and Occludable Angle: The Jiangning Eye Study. [PDF]
PLoS ONE, 2016 Myopia subjects usually have long axial lengths and are predisposed to deep anterior chamber depths and open angles. Jiangning eye study is a randomized, population based study in Shanghai to determine whether myopia has an effect on the prevalence of ...
Xiaohong Liu +9 more
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Trabecular meshwork gene expression after selective laser trabeculoplasty.
PLoS ONE, 2011 BackgroundTrabecular meshwork and Schlemm's canal are the tissues appointed to modulate the aqueous humour outflow from the anterior chamber. The impairment of their functions drives to an intraocular pressure increase.
Alberto Izzotti +4 more
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