Results 51 to 60 of about 166,926 (278)

Electrochemical immunosensor based on MWCNT-CS as a signal amplification strategy for the detection of capsaicinoids

open access: yesInternational Journal of Electrochemical Science, 2021
We constructed an electrochemical immunosensor based on multiwalled carbon nanotube-chitosan (MWCNT-CS) for on-site detection of capsaicinoids, which are label compounds in waste oils.
Fengzhen Yang   +7 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

EL-MTSA: Stock Prediction Model Based on Ensemble Learning and Multimodal Time Series Analysis

open access: yesApplied Sciences
Predicting stock prices is a popular area of study within the realms of data mining and machine learning. Precise forecasting can assist investors in mitigating the risks associated with their investments.
Jianlei Kong   +4 more
doaj   +1 more source

Optimization of Tax Collection and Administration Efficiency in Less Developed Regions of Western China

open access: yesDiscrete Dynamics in Nature and Society, 2022
Tax is the main source of national and regional income, and the efficiency of tax collection and administration is of great significance to the sustainable development.
Ke Yan   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Traceability-Why Do It? [PDF]

open access: yes, 2012
Traceability of software artifacts, from requirements to design and through implementation and quality assurance, has long been promoted by the research and expert practitioner communities. However, evidence indicates that, with the exception of those operating in the safety critical domain, few software companies choose to implement traceability ...
Regan, Gilbert   +3 more
openaire   +2 more sources

Modeling of Traceability Information System for Material Flow Control Data. [PDF]

open access: yes, 2010
This paper focuses on data modeling for traceability of material/work flow in information layer of manufacturing control system. The model is able to trace all associated data throughout the product manufacturing from order to final product.
Ismail, Md. Yusof   +3 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

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