Results 61 to 70 of about 170,536 (302)

Ensuring the visibility and traceability of items through logistics chain of automotive industry based on AutoEPCNet Usage [PDF]

open access: yes, 2016
Traceability in logistics is the capability of the participants to trace the products throughout the supply chain by means of either the product and/or container identifiers in a forward and/or backward direction.
Beneš, Filip   +7 more
core   +2 more sources

Electrochemical immunosensor based on MWCNT-CS as a signal amplification strategy for the detection of capsaicinoids

open access: yesInternational Journal of Electrochemical Science, 2021
We constructed an electrochemical immunosensor based on multiwalled carbon nanotube-chitosan (MWCNT-CS) for on-site detection of capsaicinoids, which are label compounds in waste oils.
Fengzhen Yang   +7 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

EL-MTSA: Stock Prediction Model Based on Ensemble Learning and Multimodal Time Series Analysis

open access: yesApplied Sciences
Predicting stock prices is a popular area of study within the realms of data mining and machine learning. Precise forecasting can assist investors in mitigating the risks associated with their investments.
Jianlei Kong   +4 more
doaj   +1 more source

Optimization of Tax Collection and Administration Efficiency in Less Developed Regions of Western China

open access: yesDiscrete Dynamics in Nature and Society, 2022
Tax is the main source of national and regional income, and the efficiency of tax collection and administration is of great significance to the sustainable development.
Ke Yan   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Traceability-Why Do It? [PDF]

open access: yes, 2012
Traceability of software artifacts, from requirements to design and through implementation and quality assurance, has long been promoted by the research and expert practitioner communities. However, evidence indicates that, with the exception of those operating in the safety critical domain, few software companies choose to implement traceability ...
Regan, Gilbert   +3 more
openaire   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy