Results 131 to 140 of about 164,752 (316)

Zonated Copper‐Driven Breast Cancer Progression Countered by a Copper‐Depleting Nanoagent for Immune and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Spatially resolved multiomics reveals that high‐copper zones are closely associated with tumor metastasis, immune‐desert phenotypes, and oxidative‐phosphorylation (OXPHOS)‐dependent proliferation. A targeted bacterial nanovesicle delivering copper‐depleting agents effectively reduces tumor copper levels, inhibits OXPHOS‐dependent tumor growth, and ...
Lin Chen   +16 more
wiley   +1 more source

A duplex transform heterogeneous feature fusion network for road segmentation

open access: yesScientific Reports
Detecting roads in automatic driving environments poses a challenge due to issues such as boundary fuzziness, occlusion, and glare from light. We believe that two factors are instrumental in addressing these challenges and enhancing detection performance:
Zhiyang Guo   +6 more
doaj   +1 more source

MATE: MPLS adaptive traffic engineering [PDF]

open access: green, 2002
A. Elwalid   +3 more
openalex   +1 more source

Tumoroid Model Reveals Synergistic Impairment of Metabolism by Iron Chelators and Temozolomide in Chemo‐Resistant Patient‐derived Glioblastoma Cells

open access: yesAdvanced Science, EarlyView.
This study investigates the metabolic vulnerabilities of glioblastoma (GBM), an aggressive brain tumor. Research demonstrates that iron chelation therapy, in combination with standard chemotherapy, significantly enhances the efficacy of treatment against resistant GBM cells in a 3D tumoroid model.
Meitham Amereh   +8 more
wiley   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

open access: yesAdvanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He   +6 more
wiley   +1 more source

ACCOUNT OF ROAD CONDITIONS WHILE INVESTIGATING TRAFFIC ACCIDENTS

open access: yesНаука и техника, 2010
The paper considers problems on better traffic safety at government, authority, engineering and driver activity levels, account of road conditions while investigating traffic accidents. The paper also provides road defects mentioned in forensic transport
D. D. Selioukov, I. I. Leonovich
doaj  

Spatiotemporal Demand Prediction for Bike Sharing Based on WT-ConvLSTM

open access: yesAdvances in Civil Engineering
To accurately predict the spatiotemporal demand for bike sharing, a hybrid model integrating wavelet transform (WT), long short-term memory (LSTM), and convolutional neural network (CNN) was developed, referred to as the WT-convolutional LSTM (ConvLSTM ...
Wenyun Tang   +4 more
doaj   +1 more source

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