Results 71 to 80 of about 3,598,857 (362)

An open source traffic engineering toolbox [PDF]

open access: yesComputer Communications, 2006
We present the TOTEM open source Traffic Engineering (TE) toolbox and a set of TE methods that we have designed and/or integrated. These methods cover intra-domain and inter-domain TE, IP-based and MPLS-based TE. They are suitable for network optimisation, better routing of traffic for providing QoS, load balancing, protection and restoration in case ...
H. ímit   +17 more
openaire   +6 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Multicast traffic aggregation in MPLS-based VPN networks [PDF]

open access: yes, 2007
This article gives an overview of the current practical approaches under study for a scalable implementation of multicast in layer 2 and 3 VPNs over an IP-MPLS multiservice network. These proposals are based on a well-known technique: the aggregation of
Larrabeiti López, David   +3 more
core   +2 more sources

On the Interplay of Link-Flooding Attacks and Traffic Engineering [PDF]

open access: yesCCRV, 2016
Link-flooding attacks have the potential to disconnect even entire countries from the Internet. Moreover, newly proposed indirect link-flooding attacks, such as ``Crossfire'', are extremely hard to expose and, subsequently, mitigate effectively.
Dimitrios Gkounis   +3 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Traffic Planning as a Preliminary Tool in Project Documentation for BIM

open access: yesBuildings, 2022
The paper presents a view on the possibilities of using big data in traffic planning and traffic engineering, which are used in the urban and spatial planning of cities. The question is whether the method of this design activity—especially in feasibility
Tibor Schlosser   +4 more
doaj   +1 more source

The Dynamics of Internet Traffic: Self-Similarity, Self-Organization, and Complex Phenomena

open access: yes, 2009
The Internet is the most complex system ever created in human history. Therefore, its dynamics and traffic unsurprisingly take on a rich variety of complex dynamics, self-organization, and other phenomena that have been researched for years.
Albert R.   +22 more
core   +2 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Influence of the Built Environment on Older Adults’ Travel Time: Evidence from the Nanjing Metropolitan Area, China

open access: yesLand, 2023
The built environment is among the critical factors in older adults’ travel behavior, and a favorable built environment can encourage them to travel and engage in various activities.
Jingrui Sun   +4 more
doaj   +1 more source

Semi-Oblivious Traffic Engineering with SMORE

open access: yesApplied Networking Research Workshop, 2018
Wide-area networks are expected to meet the competing objectives of high performance and reliability in the presence of various operational constraints and failures.
Praveen Kumar   +7 more
semanticscholar   +1 more source

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