Results 71 to 80 of about 3,731,861 (383)
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Planning logistics network for recyclables collection [PDF]
Yugoslav Journal of Operations Research, 2014 Rapid urbanization, intensified industrialization, rise of income, and a more sophisticated form of consumerism are leading to an increase in the amount and toxicity of waste all over the world.
Ratković Branislava +3 more
doaj +1 more source
Robust and Reactive Traffic Engineering for Dynamic Traffic Demands [PDF]
2008 Next Generation Internet Networks, 2008 Traffic engineering (TE) has become a challenging mechanism for network management and resources optimization due to uncertain and difficult to predict traffic patterns. Recent works have proposed robust optimization techniques to cope with uncertain traffic, computing a stable routing configuration that is immune to demand variations within certain ...
Casas Hernandez, Pedro +2 more
openaire +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Adaptive Robust Traffic Engineering in Software Defined Networks
, 2017 One of the key advantages of Software-Defined Networks (SDN) is the opportunity to integrate traffic engineering modules able to optimize network configuration according to traffic.
Capone, Antonio +4 more
core +1 more source
Feasibility Study of Flyover Project on R.A. Basyid Street – Untung Suropati Reviewed in Terms of Traffic and Economic Engineering [PDF]
, 2021 Alfrido Hutagalung +2 more
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 2008 In a network, traffic demands are known with a degree of uncertainty, traffic engineering should take into account the traffic variability. In this research work we focus on the robust routing under changing network conditions.
Agrawal, H +3 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multi-path Traffic Engineering Protocol Based on TeXCP [PDF]
Jisuanji gongcheng, 2018 In order to adapt to the real-time network traffic demand,and find the network fault in time,based on classic online distributed traffic engineering protocol TeXCP,this paper proposes Multi-path Traffic Engineering(MTE) protocol.The protocol consists of ...
YANG Yi,WU Zhaofeng,HU Guyu
doaj +1 more source