Results 51 to 60 of about 167,855,735 (244)

Comparative study of intubating condition between rocuronium and vecuronium for endotracheal intubation in general anesthesia

open access: yesAsian Journal of Medical Sciences
Background: Muscle relaxation in anesthesia serves two main purposes: Facilitating endotracheal intubation and achieving surgical relaxation. The period from the suppression of protective reflexes during induction to the completion of intubation is ...
Ganesh Choudhari   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Randomized prospective study to compare intubating conditions with cisatracurium or rocuronium using train-of-four neuromuscular monitoring in adult patients undergoing elective surgery

open access: yesAsian Journal of Medical Sciences
Background: Nondepolarizing skeletal muscle relaxants are used in anesthesia to ease endotracheal intubation and improve ventilation. Monitoring neuromuscular blockade is crucial to minimize residual paralysis and optimize dosing. Aims and Objectives:
Radhika Kukreja   +4 more
doaj   +1 more source

Neuromuscular blockade monitoring in pediatric patients [PDF]

open access: yesAnesthesia and Pain Medicine
Neuromuscular blocking agents (NMBAs), a cornerstone of pediatric anesthesia, facilitate intubation and muscle relaxation during surgery. However, NMBAs can also lead to serious complications including respiratory depression, residual paralysis, and ...
Zehra Serpil Ustalar Ozgen
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Four Minute Men, Women's Division, Birmingham, Alabama, scrapbook, November 1918-June 1919

open access: yes, 1918
The scrapbook was compiled by the Women's Division of the Four-Minute Men in Birmingham, Alabama. The Four-Minute Men organizations were volunteers authorized by President Woodrow Wilson's Committee on Public Information to give four-minute speeches ...
Four Minute Men (Society)
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Jubilee train.

open access: yes, 1951
Cover title.; At head of title: Commonwealth of Australia Jubilee Celebrations 1951.; Electronic reproduction. Canberra, A.C.T.
Commonwealth of Australia Jubilee, 1951. State Executive Committee of South Australia. Jubilee Train Committee.
core  

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