Results 61 to 70 of about 167,855,735 (244)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Train drivers' alcohol limit four times higher than taxi and bus drivers'.
, 2018 Current legislation which permits train drivers and other railway workers to have four times more alcohol in their blood than other professional drivers “fell between the gaps”, an Oireachtas Committee has heard.....
Burns, Sarah
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Pakistan Armed Forces Medical JournalObjective: To establish relationship between train-of-four ratio and clinical signs including head lift during emergence from general anesthesia. Study Design: Cross Sectional Study.
Syed Zeeshan Haider +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Economic impact of synthetic fuels and M-X development on small business in the four corners region
, 1981 reportThe development of asynthetic fuels industry and the deployment of the M-X nuclear weapons station within the Four Corners region raises serious questions about potential economic impacts.
Four Corners Regional Commission
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, 2008 We compare two approaches for estimating the distribution of consumers' willingness to pay (WTP) in discrete choice models. The usual procedure is to estimate the distribution of the utility coefficients and then derive the distribution of WTP, which is ...
Thiene, M +13 more
core +1 more source
French Gratitude Train visitors
, 1950 Two visitors to the French Gratitude Train looking at the display of French products and historical objects. On the wall is a poster of the Bretagne region from the French National Railroad Society.
J. Hildreth Photographs;
core +1 more source
ChildrenBackground: In adult patients, rocuronium shows interindividual variability related to weight, sex, and age, but paediatric data are limited. This study aimed to evaluate clinical factors influencing the duration of action of rocuronium in children ...
Katerina Szturzova +7 more
doaj +1 more source
Sugammadex versus neostigmine in pediatric patients: a prospective randomized study
Revista Brasileira de Anestesiologia, 2014 Background and objectives: Acetylcholinesterase inhibitors may cause postoperative residual curarization when they are used for reversal of neuromuscular blockade. Sugammadex reverses neuromuscular blockade by chemical encapsulation and is not associated
Turhan Kara +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source