Results 41 to 50 of about 105,830 (217)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Intelligent Sliding Mode Control for Quadrotor Trajectory Tracking Under External Disturbances [PDF]

This paper proposes particle swarm optimization (PSO) and cuckoo search (CS) approaches based on the sliding mode controller (SMC) structure for the unmanned quadrotor’s flights. The control law is derived from the Lyapunov theory to guarantee the closed-
Mostafa Mjahed, Abdeljalil El Kari, Nada El Gmili, Hassan Ayad, Khadija El Hamidi   +4 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Robust automatic target tracking based on a Bayesian ego-motion compensation framework for airborne FLIR imagery [PDF]

, 2009
Automatic target tracking in airborne FLIR imagery is currently a challenge due to the camera ego-motion. This phenomenon distorts the spatio-temporal correlation of the video sequence, which dramatically reduces the tracking performance.
Salgado Álvarez de Sotomayor, Luis, García Santos, Narciso, Jaureguizar Núñez, Fernando, Blanco Adán, Carlos Roberto del   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Formation control of nonholonomic mobile robots: the virtual structure approach [PDF]

, 2012
PhDIn recent years, there has been a considerable growth in applications of multi-robot systems as opposed to single-robot systems. This thesis presents our proposed solutions to a formation control problem in which mobile robots are required to ...
Sadowska, Anna Danuta
core  

Multi-camera video surveillance for real-time analysis and reconstruction of soccer games [PDF]

, 2010
Soccer analysis and reconstruction is one of the most interesting challenges for wide-area video surveillance applications. Techniques and system implementation for tracking the ball and players with multiple stationary cameras are discussed.
Orwell, James, Jones, Graeme A., Jones, G., Ren, Jinchang, Xu, Ming, Xu, M., Orwell, J.   +6 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Pre-tactical trajectory compatibility determination to reduce air traffic controllers' tactical workload [PDF]

, 2012
The current Air Traffic Management (ATM) system, based on principles established more than 50 years ago, is starting to show clear signs of saturation. This fact.
Portillo, Yolanda
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source