Results 51 to 60 of about 95,519 (265)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Behavior Trajectory Tracking of Piglets Based on DLC-KPCA
Agriculture, 2021 Tracking the behavior trajectories in pigs in group is becoming increasingly important for welfare feeding. A novel method was proposed in this study to accurately track individual trajectories of pigs in group and analyze their behavior characteristics.
Chengqi Liu +7 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
ActuatorsTo address trajectory tracking of cable-driven continuum robots (CDCRs) in the presence of obstacles, this paper proposes an integrated control framework that combines online trajectory replanning, obstacle avoidance, and tracking control.
Yanan Qin, Qi Chen
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Development of a multi-level feature fusion model for basketball player trajectory tracking
Systems and Soft ComputingTo solve the problems of low matching degree, long tracking time, and low accuracy of multi-target tracking in the process of athlete motion trajectory tracking using deep learning technology, a new athlete motion trajectory tracking model was proposed ...
Tao Wang
doaj +1 more source
Tracking the Trajectories of Genni Gunn’s Writing
Italian Canadiana, 2023 This article examines Genni Gunn’s writing in light of her childhood immigration experience and contends that, despite the crypto-ethnic approach she has adopted vis-à-vis her Italian-Canadian heritage, migration figures prominently in both her fictional and personal works, which bear traces of her autobiographical vicissitudes and reflect her own ...
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Trajectory Fusion for Multiple Camera Tracking [PDF]
, 2007 In this paper we present a robust and efficient method to overcome the negative effects of occlusion in the tracking process of multiple agents. The proposed approach is based on the matching of multiple trajectories from multiple views using spatial and temporal information.
Amato, Ariel +3 more
openaire +3 more sources