Results 11 to 20 of about 52,129 (297)
Journal of the American Medical Association (JAMA), 2021 Importance Although tramadol is increasingly used to manage chronic noncancer pain, few safety studies have compared it with other opioids. Objective To assess the associations of tramadol, compared with codeine, with mortality and other adverse ...
Junqing Xie +13 more
semanticscholar +1 more source
Pharmaceuticals, 2021 Paracetamol (acetaminophen) (PAR), caffeine (CAF) and tramadol hydrochloride (TRA) are important drugs widely used for many clinical purposes. Determination of their contents is of the paramount interest.
F. J. Pereira +4 more
semanticscholar +1 more source
Cureus, 2021 Myoclonus is a sudden, involuntary jerking of a muscle or a group of muscles. Myoclonus may present in form of a pattern or, sporadically and infrequently. It is usually associated with neurological disorders such as epilepsy, multiple sclerosis or infections, and tumors of the central nervous system.
Naila Manahil +4 more
openaire +3 more sources
Investigation of the Mechanisms of Tramadol-Induced Seizures in Overdose in the Rat
Pharmaceuticals, 2022 Tramadol overdose is frequently associated with the onset of seizures, usually considered as serotonin syndrome manifestations. Recently, the serotoninergic mechanism of tramadol-attributed seizures has been questioned.
Camille Lagard +9 more
doaj +1 more source
Full Opioid Agonists and Tramadol: Pharmacological and Clinical Considerations
Anesthesiology and Pain Medicine, 2021 Opioids are mu receptor agonists and have been an important part of pain treatment for thousands of years. In order to use these drugs appropriately and successfully in patients, whether to control pain, to treat opiate-induced side effects, or opiate ...
Amber N. Edinoff +10 more
semanticscholar +1 more source
Tramadol for osteoarthritis [PDF]
Cochrane Database of Systematic Reviews, 2019 Tramadol is often prescribed to treat pain and is associated physical disability in osteoarthritis (OA). Due to the pharmacologic mechanism of tramadol, it may lead to fewer associated adverse effects (i.e. gastrointestinal bleeding or renal problems) compared to non-steroidal anti-inflammatory drugs (NSAIDs).
Anne W S Rutjes +11 more
openaire +4 more sources
Tramadol Treatment Induces Change in Phospho-Cyclic Adenosine Monophosphate Response Element-Binding Protein and Delta and Mu Opioid Receptors within Hippocampus and Amygdala Areas of Rat Brain [PDF]
Addiction and Health, 2021 Background: Tramadol induces its unique effects through opioid pathways, but the exact mechanism is not known. The study aims to evaluate changes in the level of mu-opioid receptor (μOR), delta-opioid receptor (δOR), and phosphorylated cyclic adenosine ...
Hamid Ahmadian-Moghadam +5 more
doaj +1 more source
BMC Endocrine Disorders, 2021 Background Tramadol is a synthetic opioid and poisoning is increasing around the world day by day. Various treatments are applied for tramadol poisoning. Due to the unknown effects of tramadol poisoning and some of its treatments on blood glucose levels,
Samaneh Nakhaee +6 more
doaj +1 more source
Journal of Advanced Veterinary and Animal Research, 2021 Opioids are considered the gold standard to manage acute or chronic or mild to severe pain. Tramadol is a widely prescribed analgesic drug for dogs and cats; it has a synthetic partial agonism on μ-opioid receptors and inhibits the reuptake of ...
A. Domínguez-Oliva +3 more
semanticscholar +1 more source
Factors Affecting Tramadol-Associated Seizure
International Journal of Medical Toxicology and Forensic Medicine, 2020 Background: Tramadol is a widely prescribed analgesic and due to its opioid-like effects, the potential for abuse of tramadol is noticeable. Besides, the complications of tramadol abuse have become a public health concern. This study aimed to investigate
Maryam Zaare Nahandi +4 more
doaj +1 more source