Results 11 to 20 of about 67,803 (253)
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023 Background Arterial hypertension, cigarette smoking, excessive alcohol abuse and drug addiction such as cocaine all are known risk factors for aneurysmal subarachnoid hemorrhage (SAH).
Ahmed Elbassiony +7 more
doaj +1 more source
Advanced Biomedical Research, 2022 Background: CA1, as a major structure involved in learning and memory, has been shown to be affected by tramadol addiction. Both orexin and endocannabinoid receptors express in CA1 and play an important role in drug dependency.
Vajihe Imanpour, Parham Reisi
doaj +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Administration of Tramadol or Buprenorphine via the drinking water for post-operative analgesia in a mouse-osteotomy model [PDF]
, 2019 Adequate analgesia is essential whenever pain might occur in animal experiments. Unfortunately, the selection of suitable analgesics for mice in bone-linked models is limited. Here, we evaluated two analgesics - Tramadol [0.1 mg/ml (Tlow) vs.
Buttgereit, Frank +7 more
core +1 more source
Pharmacokinetics and antinociceptive effects of tramadol and its metabolite O-desmethyltramadol following intravenous administration in sheep [PDF]
, 2015 Although sheep are widely used as an experimental model for various surgical procedures there is a paucity of data on the pharmacokinetics and efficacy of analgesic drugs in this species. The aims of this study were to investigate the pharmacokinetics of
A., Di Salvo +6 more
core +1 more source
Electrochemical determination of tramadol using modified screen printed electrode
Journal of Electrochemical Science and Engineering, 2021 The detection of tramadol using a screen printed electrode modified with La3+/ZnO nano-flowers and multi-walled carbon nanotubes (La3+/ZnO NFs-MWCNTs/SPE) is reported in this work.
Sayed ali Ahmadi +4 more
doaj +1 more source
Determination of Tramadol in human plasma by HPLC with fluorescence detection [PDF]
, 2016 Tramadol is a centrally acting analgesic, atypical opioid, and although it is generally considered as a medicinal drug with a low potential for dependence, there is growing evidence of tramadol abuse in some countries.
Abdul Jalil Ebrahim, Zainab +4 more
core +3 more sources
Jurnal Anestesi Perioperatif, 2019 Analgesia multimodal adalah prinsip manajemen nyeri pascaoperasi. Penelitian ini merupakan uji klinis rancangan acak tersamar ganda. Tujuan penelitian ini membandingkan efek kombinasi analgesik tramadol dan deksketoprofen dengan tramadol dan parasetamol ...
Clara Valentia Josephine +3 more
doaj +1 more source
Chronic exposure to tramadol induces cardiac inflammation and endothelial dysfunction in mice
Scientific Reports, 2021 Tramadol is an opioid extensively used to treat moderate to severe pain; however, prolonged therapy is associated with several tissues damage. Chronic use of tramadol was linked to increased hospitalizations due to cardiovascular complications.
Marwa H. Bakr +6 more
doaj +1 more source
Physiology-based IVIVE predictions of tramadol from in vitro metabolism data [PDF]
, 2014 To predict the tramadol in vivo pharmacokinetics in adults by using in vitro metabolism data and an in vitro-in vivo extrapolation (IVIVE)-linked physiologically-based pharmacokinetic (PBPK) modeling and simulation approach (SimcypA (R)).
Allegaert, Karel +10 more
core +1 more source