Results 11 to 20 of about 94,263 (328)

Administration of Tramadol or Buprenorphine via the drinking water for post-operative analgesia in a mouse-osteotomy model [PDF]

open access: yesScientific Reports, 2019
Adequate analgesia is essential whenever pain might occur in animal experiments. Unfortunately, the selection of suitable analgesics for mice in bone-linked models is limited. Here, we evaluated two analgesics - Tramadol [0.1 mg/ml (Tlow) vs.
Buttgereit, Frank   +7 more
core   +2 more sources

A Systematic Review of Laboratory Evidence for the Abuse Potential of Tramadol in Humans

open access: yesFrontiers in Psychiatry, 2019
Background: Tramadol is an opioid-analgesic that has shown epidemiological evidence of abuse. This review evaluates the evidence for tramadol abuse potential in humans.Methods: A systematic literature search for human abuse liability examinations of ...
Kelly E. Dunn   +3 more
doaj   +2 more sources

Retrospective analysis reveals significant association of hypoglycemia with tramadol and methadone in contrast to other opioids. [PDF]

open access: yesScientific Reports, 2019
Tramadol is one of the most commonly used analgesics worldwide, classified as having a low abuse potential by U.S. Drug Enforcement Agency, and often recommended in pain management guidelines.
Abagyan, Ruben   +3 more
core   +3 more sources

Full Opioid Agonists and Tramadol: Pharmacological and Clinical Considerations

open access: diamondAnesthesiology and Pain Medicine, 2021
Opioids are mu receptor agonists and have been an important part of pain treatment for thousands of years. In order to use these drugs appropriately and successfully in patients, whether to control pain, to treat opiate-induced side effects, or opiate ...
Amber N. Edinoff   +10 more
openalex   +3 more sources

A UiO-66-NH2 MOF/PAMAM Dendrimer Nanocomposite for Electrochemical Detection of Tramadol in the Presence of Acetaminophen in Pharmaceutical Formulations

open access: yesBiosensors, 2023
In this work, we prepared a novel electrochemical sensor for the detection of tramadol based on a UiO-66-NH2 metal–organic framework (UiO-66-NH2 MOF)/third-generation poly(amidoamine) dendrimer (G3-PAMAM dendrimer) nanocomposite drop-cast onto a glassy ...
Fariba Garkani Nejad   +2 more
semanticscholar   +1 more source

A review on tramadol toxicity: mechanism of action, clinical presentation, and treatment

open access: yesForensic Toxicology, 2021
As an analgesic that acts upon the central nervous system (CNS), tramadol has gained popularity in treating moderate to severe pain. Recently, it has been increasingly reported as a drug of misuse with intentional overdoses or intoxications.
S. Nakhaee   +5 more
semanticscholar   +1 more source

Increase of high‐risk tramadol use and harmful consequences in France from 2013 to 2018: Evidence from the triangulation of addictovigilance data

open access: yesBritish Journal of Clinical Pharmacology, 2022
The aim of this paper is to assess recent developments in non‐medical tramadol use, tramadol use disorder, illegal procurement and deaths.
A. Roussin   +8 more
semanticscholar   +1 more source

Celecoxib‐tramadol co‐crystal in patients with moderate‐to‐severe pain following bunionectomy with osteotomy: A phase 3, randomized, double‐blind, factorial, active‐ and placebo‐controlled trial

open access: yesPain Practice, 2022
Celecoxib‐tramadol co‐crystal (CTC) is a first‐in‐class analgesic co‐crystal of celecoxib and racemic tramadol with an improved pharmacologic profile, conferred by the co‐crystal structure, compared with its active constituents administered alone ...
E. Viscusi   +16 more
semanticscholar   +1 more source

Development and Validation of an RP-HPLC-PDA Method for Determination of Paracetamol, Caffeine and Tramadol Hydrochloride in Pharmaceutical Formulations

open access: yesPharmaceuticals, 2021
Paracetamol (acetaminophen) (PAR), caffeine (CAF) and tramadol hydrochloride (TRA) are important drugs widely used for many clinical purposes. Determination of their contents is of the paramount interest.
F. J. Pereira   +4 more
semanticscholar   +1 more source

The Insurgence of Tramadol Abuse among the Most Active Population in Jirapa Municipality: A Study to Assess the Magnitude of the Abuse and Its Contributory Factors

open access: yesPsychiatry Journal, 2021
Background Tramadol has gained popularity among the drugs of the most active population especially the respondents in Ghana abuse especially farmers who nicknamed as “farm and buy cow.” It has recently become a public health concern, and stakeholders are
Ferguson Saapiire   +3 more
semanticscholar   +1 more source

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