Results 31 to 40 of about 37,856 (275)

The influence of tramadol and parecoxib on erythmyocin or bleomycin-induced pleurodesis in rabbit: a pilot study [PDF]

open access: yes, 2021
Introduction: Recurrent pleural effusion secondary to advanced malignant diseases can lead to poor quality of life, recurrent hospital stays and increased hospital costs, which has yet to be extensively explored.
Nik Amin Sahid Nik Lah   +6 more
core   +1 more source

Tramadol-induced hepato- and nephrotoxicity in rats: Role of Curcumin and Gallic acid as antioxidants - Fig 3

open access: yes, 2018
A and B are photomicrographs of kidney sections of the control group that showed normal renal tissues of glomeruli and tubules (H&E 200). Fig 3C is the photomicrograph of kidney section of tramadol-treated group after single dose treatment and showed ...
Sabah G. El-Banna (5635181)   +2 more
core   +1 more source

Analgesic Effects of Repetitive Transcranial Magnetic Stimulation at Different Stimulus Parameters for Neuropathic Pain: A Randomized Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The aim of the present study was to investigate the analgesic effects of repetitive transcranial magnetic stimulation over the primary motor cortex (M1‐rTMS) using different stimulation parameters to explore the optimal stimulus condition for treating neuropathic pain.
Nobuhiko Mori   +5 more
wiley   +1 more source

Impact of Chronic Tramadol Intake on Reproductive Hormones and Related Histopathological Changes in Adult Albino Rats [PDF]

open access: yesAin Shams Journal of Forensic Medicine and Clinical Toxicology, 2020
Background: Tramadol is a synthetic opioid analgesic, widely used in the treatment of osteoarthritis, back pain, sports injuries, and other musculo-skeletal conditions, rheumatological conditions, and headaches.
Suzi Atallah   +4 more
doaj   +1 more source

Integrated analysis of WGCNA and machine learning identified diagnostic biomarkers in trauma-induced coagulopathy

open access: yesScientific Reports
Despite advancements in trauma care, uncontrolled hemorrhage and trauma-induced coagulopathy (TIC) remain the leading causes of preventable deaths after trauma.
Qingsong Chen   +18 more
doaj   +1 more source

Protective role of CoQ10 in reducing the side effects resulting from the use of Tramadol on some immunological variables in the endemic female rabbits

open access: yesTikrit Journal of Pure Science, 2023
The aim of study to determine out the role of CoQ10 in reducing the side effects from the use of Tramadol on the level of Interlukin IL-6, IL-10 and PGF2α the study included 30 endemic female rabbits, where each group included  5 animals.
Hanan Shihab Ahmad Hussain   +2 more
doaj   +1 more source

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins   +23 more
wiley   +1 more source

Comparative bioequivalence studies of tramadol hydrochloride sustained-release 200 mg tablets

open access: yes, 2010
Suhas S Khandave1, Satish V Sawant1, Santosh S Joshi1, Yatish K Bansal2, Sonal S Kadam21Accutest Research Laboratories (I) Private Limited, Koparkhirne, Navi Mumbai, Maharashtra, India; 2Ipca Laboratories Limited, Kandivli Mumbai, Maharashtra ...
Khandave Suhas   +8 more
core   +1 more source

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis   +5 more
wiley   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval   +6 more
wiley   +1 more source

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