Results 41 to 50 of about 13,664 (199)

Impact of Chronic Tramadol Intake on Reproductive Hormones and Related Histopathological Changes in Adult Albino Rats [PDF]

Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2020
Background: Tramadol is a synthetic opioid analgesic, widely used in the treatment of osteoarthritis, back pain, sports injuries, and other musculo-skeletal conditions, rheumatological conditions, and headaches.
Suzi Atallah, Asmaa Ali, Soha Ashry, Nahla Tolba, Mona Moussa   +4 more
doaj   +1 more source

Tramadol-induced hepato- and nephrotoxicity in rats: Role of Curcumin and Gallic acid as antioxidants - Fig 2

, 2018
A and B are photomicrograph of livers of control rats (H&E 200 & 100.); (c) Photomicrograph of liver section of tramadol-treated group after single dose revealing mild vacuolar degeneration of hepatic cells (pink arrow) (H&E 200).
Sabah G. El-Banna (5635181), Salah A. Sheweita (3324807), Ainour A. Almasmari (5635178)   +2 more
core   +1 more source

Comparison of tramadol, tramadol-metamizol and tramadol-lornoxicam administered by intravenous PCA in management of postoperative pain [PDF]

, 2007
Comparison of tramadol, tramadol-metamizol and tramadol-lornoxicam administered by intravenous PCA in management of postoperative pain. The aim of the present study was to compare of the postoperative analgesic effects of tramadol, combinations of ...
Kemal, Sibel Ozcakir, Sahin, Saziye, Apan, Alparslan   +2 more
core   +1 more source

Tramadol-induced hepato- and nephrotoxicity in rats: Role of Curcumin and Gallic acid as antioxidants - Fig 3

, 2018
A and B are photomicrographs of kidney sections of the control group that showed normal renal tissues of glomeruli and tubules (H&E 200). Fig 3C is the photomicrograph of kidney section of tramadol-treated group after single dose treatment and showed ...
Sabah G. El-Banna (5635181), Salah A. Sheweita (3324807), Ainour A. Almasmari (5635178)   +2 more
core   +1 more source

Integrated analysis of WGCNA and machine learning identified diagnostic biomarkers in trauma-induced coagulopathy

Scientific Reports
Despite advancements in trauma care, uncontrolled hemorrhage and trauma-induced coagulopathy (TIC) remain the leading causes of preventable deaths after trauma.
Qingsong Chen, Tao Li, Tao Zhang, Yue Zhou, Weifeng Huang, Hui Li, Li Shi, Jianxiao Li, Qi Zhang, Man Ma, Pan Wang, Hui Hu, Gongbin Wei, Jiangxia Xiang, Yuan Cheng, Jun Yang, Guangbin Huang, Yongming Li, Dingyuan Du   +18 more
doaj   +1 more source

Protective role of CoQ10 in reducing the side effects resulting from the use of Tramadol on some immunological variables in the endemic female rabbits

Tikrit Journal of Pure Science, 2023
The aim of study to determine out the role of CoQ10 in reducing the side effects from the use of Tramadol on the level of Interlukin IL-6, IL-10 and PGF2α the study included 30 endemic female rabbits, where each group included  5 animals.
Hanan Shihab Ahmad Hussain, Zaid M.Mubark AL-Mahdawi, Muneef Saab Ahmed Aljanabi   +2 more
doaj   +1 more source

The impact of medication shortages on paediatric care: A retrospective impact analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Medication shortages are a growing global concern, with potentially greater consequences in paediatric patients because of the limited availability of safe, evidence‐based and appropriately formulated medication. This study aimed to evaluate the impact of medication shortages on paediatric patients by assessing the suitability and safety of ...
Maaike Johanna Rutten ‐ van Kranenburg, Laurens Christiaan van Rijn, Elisabeth Johanna Ruijgrok, Sinno Henricus Paulus Simons, Brigitta Carolina Maria Witjes, Jan‐Dietert Christoffer Brugma, Robert Bernard Flint   +6 more
wiley   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source

Analgesic Effects of Repetitive Transcranial Magnetic Stimulation at Different Stimulus Parameters for Neuropathic Pain: A Randomized Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The aim of the present study was to investigate the analgesic effects of repetitive transcranial magnetic stimulation over the primary motor cortex (M1‐rTMS) using different stimulation parameters to explore the optimal stimulus condition for treating neuropathic pain.
Nobuhiko Mori, Koichi Hosomi, Asaya Nishi, Satoru Oshino, Haruhiko Kishima, Youichi Saitoh   +5 more
wiley   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source