Results 51 to 60 of about 68,585 (257)

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

Prevalence and factors associated with tramadol use among university students in Ghana: a cross-sectional survey

BMC Psychiatry
Background There are progressively alarming rates of non-medical use, addiction and possible dependence on tramadol in low-middle-income countries.
Joseph Lasong, Yula Salifu, Jonas Assani wa Mwenda Kakungu   +2 more
doaj   +1 more source

PENGARUH PEMBERIAN ANALGESIK KOMBINASI PARASETAMOL DAN TRAMADOL TERHADAP KADAR KREATININ SERUM TIKUS WISTAR

Jurnal Kedokteran Diponegoro, 2016
Latar Belakang : Kombinasi parasetamol dan tramadol merupakan analgesik kombinasi yang ideal dan efektif dalam menangani nyeri derajat sedang sampai berat.
Gianita Puspita Dewi, Taufik Eko Nugroho
doaj   +1 more source

Silymarin extract modulates toxicity, injury, oxidative stress, and PCNA alternations induced by tramadol in rat liver [PDF]

Journal of Bioscience and Applied Research, 2017
Tramadol is a synthetic opioid analgesic commonly prescribed for moderate to severe pain. This study was designed to evaluate the effects of silymarin supplementation on Tramadol induce injury, oxidative stress, and PCNA expression alterations on the ...
Nadhom Khalaf
doaj   +1 more source

Efeitos do tramadol sobre variáveis clínicas e limiar nociceptivo mecânico em equinos [PDF]

, 2014
Avaliaram-se os efeitos clínicos e o potencial antinociceptivo mecânico de diferentes doses de tramadol administradas por via intravenosa (IV) em equinos.
Franco, Leandro Guimarães, Moreno, Juan Carlos Duque, Silva, Luiz Antônio Franco da, Souza, Moisés Caetano e, Teixeira Neto, Antônio Raphael   +4 more
core   +3 more sources

Impact of secured prescription implementation on ambulatory pregabalin use in France: A regional assessment in the French Nouvelle‐Aquitaine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The French authorities mandated the use of secure prescriptions for pregabalin on May 2021. This study aimed to evaluate the impact of this measure on pregabalin use and misuse in Nouvelle‐Aquitaine, a southwestern French region with around six million inhabitants.
Maika Munech‐Herran, Véronique Moysan, Bruno Lescarret, Clément Mathieu, Antoine Pariente, Nicolas Rousselot   +5 more
wiley   +1 more source

Comparison of tramadol, lidocaine and tramadol-lidocaine combination for epidural analgesia in goats

Journal of Veterinary Medical Research, 2017
The aim of this study was to compare the analgesic effect of tramadol, lidocaine and tramadol-lidocaine combination injected in the epidural space in goats.
Ragab G. H., Seif M. M, Fatma M. Halfaya
doaj  

PENGARUH PEMBERIAN ANALGESIK KOMBINASI PARASETAMOL DAN TRAMADOL TERHADAP KADAR SERUM GLUTAMAT PIRUVAT TRANSAMINASE

Jurnal Kedokteran Diponegoro, 2017
Latar Belakang : Kombinasi parasetamol dan tramadol merupakan analgesik kombinasi yang ideal dan efektif dalam menangani nyeri derajat sedang sampai berat. Keduanya bekerja pada mekanisme berbeda dalam penangan nyeri.
Peggy Rahmat Syahputra, Taufik Eko Nugroho   +1 more
doaj   +1 more source

Severe complications of tramadol overdose in Iran [PDF]

Epidemiology and Health, 2019
OBJECTIVES Severe complications of tramadol overdose have been reported; however, few large-scale studies have investigated this issue. Therefore, this study aimed to explore the presentation and complications of tramadol overdose in patients admitted to
Paria Habibollahi, Alireza Garjani, Samad Shams Vahdati, Seyyed-Reza Sadat-Ebrahimi, Neda Parnianfard   +4 more
doaj   +1 more source

Current evidence for a modulation of low back pain by human genetic variants [PDF]

, 2009
The manifestation of chronic back pain depends on structural, psychosocial, occupational and genetic influences. Heritability estimates for back pain range from 30% to 45%. Genetic influences are caused by genes affecting intervertebral disc degeneration
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core   +1 more source