Results 51 to 60 of about 37,856 (275)

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

Drug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis, Helen G. Gika, Georgios Panagiotoglou, Eleni Parlapani, Pavlos Pavlidis, Nikolaos Raikos   +5 more
wiley   +1 more source

Prevalence and factors associated with tramadol use among university students in Ghana: a cross-sectional survey

BMC Psychiatry
Background There are progressively alarming rates of non-medical use, addiction and possible dependence on tramadol in low-middle-income countries.
Joseph Lasong, Yula Salifu, Jonas Assani wa Mwenda Kakungu   +2 more
doaj   +1 more source

“Here in Ghana hard work don’t deserve money”: The uncertainty and precarity of youth who use tramadol

SSM: Qualitative Research in Health, 2022
There has been a global rise in problematic non-medical use of prescription medication. In West Africa, recent media reports have highlighted increases in the use of tramadol especially among youth. In Ghana, current framings of this issue have described
Jacob Albin Korem Alhassan
doaj   +1 more source

Tramadol and o-desmethyl tramadol clearance maturation and disposition in humans: a pooled pharmacokinetic study.

, 2015
BACKGROUND AND OBJECTIVES We aimed to study the impact of size, maturation and cytochrome P450 2D6 (CYP2D6) genotype activity score as predictors of intravenous tramadol disposition. METHODS Tramadol and O-desmethyl tramadol (M1) observations in
Beier, Horst, Holford, Sam, de Hoon, Jan N, Troconiz, Inaki, Holford, Nick, Anderson, Brian J, Anderson, Brian, de Hoon, Jan, Stamer, Ulrike, Pedersen, Rasmus S, Rochette, Alain, Allegaert, Karel, Trocóniz, Iñaki F, Stuber, Frank, Pedersen, Rasmus S.   +14 more
core   +1 more source

Examining the Effects of Tramadol, on the WADA Prohibited List, on Sports Performance [PDF]

Tramadol, an opioid analgesic, was added to the World Anti-Doping Agency (WADA) Prohibited List in 2024. Tramadol has been widely used by athletes to manage sports-related pain.
Aysun Hacışevki, Cemre Acar Halıcı
core   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Tramadol Induced Adrenal Insufficiency: Histological, Immunohistochemical, Ultrastructural, and Biochemical Genetic Experimental Study

Journal of Toxicology, 2017
Tramadol is a synthetic, centrally acting analgesic. It is the most consumed narcotic drug that is prescribed in the world. Tramadol abuse has dramatically increased in Egypt. Long term use of tramadol can induce endocrinopathy. So, the aim of this study
Shereen Abdelhakim Abdelaleem, Osama A. Hassan, Rasha F. Ahmed, Nagwa M. Zenhom, Rehab A. Rifaai, Nashwa F. El-Tahawy   +5 more
doaj   +1 more source

Tramadol dependence: A case series from India

Indian Journal of Psychological Medicine, 2012
Tramadol is an atypical, centrally acting, synthetic analgesic, acting through opioid and non-opioid systems. We present a series of seven cases, all men, who sought treatment at our centre for tramadol-dependence.
Siddharth Sarkar, Naresh Nebhinani, Shubh M Singh, Surendra K Mattoo, Debasish Basu   +4 more
doaj   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

Journal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis, Kelly Galisteu‐Luiz, Gabriela Leite Pedroso, Gustavo Lopes Puls, Leticia Cassaro, Bruno Boaventura Vieira, Fábio Lourenço Romano, Erika Calvano Küchler, Christian Kirschneck, Daniela Silva Barroso de Oliveira, Maria Bernadete Sasso Stuani, Mirian Aiko Nakane Matsumoto   +11 more
wiley   +1 more source

Age‐related local versus systemic early phase wound healing dynamics following free gingival graft harvest

Journal of Periodontology, EarlyView.
Abstract Background Free palatal gingival grafts (FGG) are commonly harvested during mucogingival procedures. The present study investigates age‐related local and systemic early secondary wound healing outcomes, following FGG harvest in a rat model. Methods A 4.2 mm diameter defect was created in the palate of 24 younger (2 m) and 24 older (6 m) Wistar
Maayan Atzmon‐Shavit, Marilena Vered, Michael Saminsky, Liat Chaushu   +3 more
wiley   +1 more source