Results 51 to 60 of about 13,664 (199)

Effects of Dependence of Tramadol, Diazepam and Their Combination on the Brain of Albino Rats: Biochemical, Histological and Immunohistochemical Study [PDF]

open access: yesAin Shams Journal of Forensic Medicine and Clinical Toxicology, 2014
Introduction: Nowadays tramadol is the most common drug of abuse. Egyptian surveys found a gradual increase in the use of tramadol among Egyptians. It has been associated with a wide range of drug abuse such as benzodiazepines.
Hayam Aiad   +5 more
doaj   +1 more source

“Here in Ghana hard work don’t deserve money”: The uncertainty and precarity of youth who use tramadol

open access: yesSSM: Qualitative Research in Health, 2022
There has been a global rise in problematic non-medical use of prescription medication. In West Africa, recent media reports have highlighted increases in the use of tramadol especially among youth. In Ghana, current framings of this issue have described
Jacob Albin Korem Alhassan
doaj   +1 more source

Comparative bioequivalence studies of tramadol hydrochloride sustained-release 200 mg tablets

open access: yes, 2010
Suhas S Khandave1, Satish V Sawant1, Santosh S Joshi1, Yatish K Bansal2, Sonal S Kadam21Accutest Research Laboratories (I) Private Limited, Koparkhirne, Navi Mumbai, Maharashtra, India; 2Ipca Laboratories Limited, Kandivli Mumbai, Maharashtra ...
Khandave Suhas   +8 more
core   +1 more source

Gabapentin as an add‐on analgesic to morphine in paediatric patients with chronic pain

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Off‐label use of gabapentin for the treatment of chronic pain in children has increased over the last decade, with multiple clinical trials evaluating its role pain management and potential opioid‐sparing effects. To date, however, these studies appear to rely on empirical evidence without further consideration of pharmacokinetic‐pharmacodynamic ...
Paul Healy   +15 more
wiley   +1 more source

Exploring the potential use of melatonin as a modulator of tramadol-induced rewarding effects in rats

open access: yesFrontiers in Pharmacology
Background:Melatonin is responsible for regulating the sleep-wake cycle and circadian rhythms in mammals. Tramadol, a synthetic opioid analgesic, is used to manage moderate to severe pain but has a high potential for abuse and dependence.
Alqassem Y. Hakami   +4 more
doaj   +1 more source

Examining the Effects of Tramadol, on the WADA Prohibited List, on Sports Performance [PDF]

open access: yes
Tramadol, an opioid analgesic, was added to the World Anti-Doping Agency (WADA) Prohibited List in 2024. Tramadol has been widely used by athletes to manage sports-related pain.
Aysun Hacışevki   +3 more
core   +1 more source

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Patterns and social factors associated with non-prescription use of Tramadol: a cross-sectional study among youth in urban informal settlements in Ghana

open access: yesJournal of Health, Population and Nutrition
Background Non-prescription use of Tramadol is increasingly becoming common among vulnerable populations. This study examines the factors associated with non-prescription use of Tramadol among youth in urban informal settlements in the Asokore Mampong ...
Solomon Osei-Tutu   +5 more
doaj   +1 more source

Remifentanil and tramadol

open access: yesBritish Journal of Anaesthesia, 1998
The lack of analgesic efficacy limits tramadol as a sole agent to treat severe pain after surgery. However, it has a relative lack of respiratory depressant and constipating effects compared with morphine and codeine, and does not share the propensity of nonsteroidal anti-inflammatory drugs to provoke asthma, gastrointestinal mucosal damage and renal ...
openaire   +2 more sources

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai   +12 more
wiley   +1 more source

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