Ameliorative Effect of Nigella Sativa on Tramadol-Induced Testicular Toxicity in Adult Rats [PDF]
Egyptian Society of Clinical Toxicology Journal, 2022 Background: Tramadol abuse is a major health problem in Egypt. It promotes oxidative stress via lowering the antioxidant levels. Nigella sativa (NS) possesses strong antioxidant properties.
Reham Eldemerdash Ibrahim +3 more
doaj +1 more source
Comparison of tramadol, lidocaine and tramadol-lidocaine combination for epidural analgesia in goats [PDF]
Journal of Veterinary Medical Research, 2017 The aim of this study was to compare the analgesic effect of tramadol, lidocaine and tramadol-lidocaine combination injected in the epidural space in goats.
Ragab G. H., Seif M. M, Fatma M. Halfaya
doaj +2 more sources
Effects of the Concomitant Administration of Thyme and Tramadol on the Cerebellar Cortex of Adult Male Albino Rat [PDF]
The Egyptian Journal of Histology, 2023 Introduction: Tramadol is a centrally acting opioid analgesic that used to relief pain. Although tramadol is thought to have low dependence potentials, it is used in acute or chronic pain, including postoperative, gynecologic and obstetric pain, as well ...
Mohamed Mohamed +3 more
doaj +1 more source
Tramadol Treatment Induces Change in Phospho-Cyclic Adenosine Monophosphate Response Element-Binding Protein and Delta and Mu Opioid Receptors within Hippocampus and Amygdala Areas of Rat Brain [PDF]
Addiction and Health, 2021 Background: Tramadol induces its unique effects through opioid pathways, but the exact mechanism is not known. The study aims to evaluate changes in the level of mu-opioid receptor (μOR), delta-opioid receptor (δOR), and phosphorylated cyclic adenosine ...
Hamid Ahmadian-Moghadam +5 more
doaj +1 more source
Brazilian Journal of Anesthesiology, 2015 Background and objectives: Tramadol is known as a central acting analgesic drug, used for the treatment of moderate to severe pain. Local analgesic effect has been demonstrated, in part due to local anesthetic-like effect, but other mechanisms remain ...
Angela Maria Sousa, Hazem Adel Ashmawi
doaj +3 more sources
Investigation of the Mechanisms of Tramadol-Induced Seizures in Overdose in the Rat
Pharmaceuticals, 2022 Tramadol overdose is frequently associated with the onset of seizures, usually considered as serotonin syndrome manifestations. Recently, the serotoninergic mechanism of tramadol-attributed seizures has been questioned.
Camille Lagard +9 more
doaj +1 more source
Histological and Immunohistochemical Study on the Effect of Tramadol Abuse on Cerebral Cortex and Hippocampus in Male Albino Rabbits [PDF]
The Egyptian Journal of Histology, 2020 Background: Tramadol is an analgesic used in moderate and severe pain however, tramadol abuse among adolescence leads to various alterations in brain histological structure that leads to psychiatric and physical abnormalities.Aim of the Work: This study ...
Hanan Elkerdasy, nehal shaheen
doaj +1 more source
BMC Endocrine Disorders, 2021 Background Tramadol is a synthetic opioid and poisoning is increasing around the world day by day. Various treatments are applied for tramadol poisoning. Due to the unknown effects of tramadol poisoning and some of its treatments on blood glucose levels,
Samaneh Nakhaee +6 more
doaj +1 more source
American Journal of Men's Health, 2021 This network meta-analysis aimed at assessing the influence of tramadol on the intravaginal ejaculatory latency time (IELT) and sexual satisfaction score (SSS) in treating patients with premature ejaculation (PE).
Youyi Lu MD +5 more
doaj +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source