Results 21 to 30 of about 52,129 (297)

The Insurgence of Tramadol Abuse among the Most Active Population in Jirapa Municipality: A Study to Assess the Magnitude of the Abuse and Its Contributory Factors

Psychiatry Journal, 2021
Background Tramadol has gained popularity among the drugs of the most active population especially the respondents in Ghana abuse especially farmers who nicknamed as “farm and buy cow.” It has recently become a public health concern, and stakeholders are
Ferguson Saapiire, Godfrey Namillah, V. Tanye, Abdulai Abubakari   +3 more
semanticscholar   +1 more source

Local analgesic effect of tramadol is not mediated by opioid receptors in early postoperative pain in rats

Brazilian Journal of Anesthesiology, 2015
Background and objectives: Tramadol is known as a central acting analgesic drug, used for the treatment of moderate to severe pain. Local analgesic effect has been demonstrated, in part due to local anesthetic-like effect, but other mechanisms remain ...
Angela Maria Sousa, Hazem Adel Ashmawi
doaj   +3 more sources

The Influence of Tramadol on Intravaginal Ejaculatory Latency Time and Sexual Satisfaction Score in Treating Patients With Premature Ejaculation: A Network Meta-Analysis

American Journal of Men's Health, 2021
This network meta-analysis aimed at assessing the influence of tramadol on the intravaginal ejaculatory latency time (IELT) and sexual satisfaction score (SSS) in treating patients with premature ejaculation (PE).
Youyi Lu MD, Zhongbao Zhou MD, Xiaoyi Zhang MD, Yuanshan Cui MD, Yong Zhang MD, Yongqiang Wang MD   +5 more
doaj   +1 more source

The frequency and impact of tramadol addiction on acute aneurysmal subarachnoid hemorrhage: cross-sectional multicenter study

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023
Background Arterial hypertension, cigarette smoking, excessive alcohol abuse and drug addiction such as cocaine all are known risk factors for aneurysmal subarachnoid hemorrhage (SAH).
Ahmed Elbassiony, Eman M. Khedr, Ahmed Hegazy, Omar Abdelaleem Ragab, Hieder Al-Shami, Radwa K. Soliman, Ahmed Shoyb, Ahmed Aly   +7 more
doaj   +1 more source

Protective role of CoQ10 in reducing the side effects resulting from the use of Tramadol on some immunological variables in the endemic female rabbits

Tikrit Journal of Pure Science, 2023
The aim of study to determine out the role of CoQ10 in reducing the side effects from the use of Tramadol on the level of Interlukin IL-6, IL-10 and PGF2α the study included 30 endemic female rabbits, where each group included  5 animals.
Hanan Shihab Ahmad Hussain, Zaid M.Mubark AL-Mahdawi, Muneef Saab Ahmed Aljanabi   +2 more
doaj   +1 more source

Association of Tramadol With All-Cause Mortality Among Patients With Osteoarthritis

Journal of the American Medical Association (JAMA), 2019
Importance An American Academy of Orthopaedic Surgeons guideline recommends tramadol for patients with knee osteoarthritis, and an American College of Rheumatology guideline conditionally recommends tramadol as first-line therapy for patients with knee ...
C. Zeng, M. Dubreuil, Marc R. Larochelle, N. Lu, Jie Wei, Hyon K. Choi, G. Lei, Yuqing Zhang   +7 more
semanticscholar   +1 more source

Perbandingan Intensitas Nyeri dan Kadar Prostaglandin Kombinasi Tramadol dan Deksketoprofen dengan Tramadol dan Parasetamol Intravena pada Pasien Bedah Ortopedi Ekstremitas Bawah

Jurnal Anestesi Perioperatif, 2019
Analgesia multimodal adalah prinsip manajemen nyeri pascaoperasi. Penelitian ini merupakan uji klinis rancangan acak tersamar ganda. Tujuan penelitian ini membandingkan efek kombinasi analgesik tramadol dan deksketoprofen dengan tramadol dan parasetamol ...
Clara Valentia Josephine, Muhammad Ramli Ahmad, Hisbullah Hisbullah, Abdul Wahab   +3 more
doaj   +1 more source

The effect of orexin-2 and endocannabinoid-1 antagonists on neuronal activity of hippocampal CA1 pyramidal neurons in response to tramadol in rats

Advanced Biomedical Research, 2022
Background: CA1, as a major structure involved in learning and memory, has been shown to be affected by tramadol addiction. Both orexin and endocannabinoid receptors express in CA1 and play an important role in drug dependency.
Vajihe Imanpour, Parham Reisi
doaj   +1 more source

The Pharmacology of Tramadol

Drugs, 1994
(+/-)-Tramadol is a central analgesic with low affinity for opioid receptors. The rate of production of its M1 metabolite (O-demethyl tramadol) is influenced by debrisoquine-type polymorphism, and this metabolite shows a higher affinity for opioid receptors than the parent drug.
Dayer, P, Collart Leemann, Laurence, Desmeules, Jules Alexandre   +2 more
openaire   +4 more sources

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source