Results 71 to 80 of about 52,129 (297)
British Journal of Clinical Pharmacology, EarlyView.Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová +6 more
wiley +1 more source
Psychosis following Tramadol Withdrawal [PDF]
Addiction and Health, 2010 Background: Tramadol is a centrally acting opioid analgesic used to treat moderate to sever pain. It has more advantage and less opioid adverse effects than conventional opioid analgesia.
Ghodratolah Rajabizadeh +2 more
doaj
Hepatotoxic Assessment of Tramadol-Diclofenac Use: A Study in a Rat Model
Biology, Medicine & Natural Product Chemistry, 2019 The concurrent use of tramadol and diclofenac may increase hepatotoxic risk due to their individual hepatotoxic effects. This study assessed the hepatotoxic effect of tramadol-diclofenac administration in albino rats.
Elias Adikwu, Ebinyo Clemente Nelson
doaj +1 more source
Combination vs. single‐drug nonprescription analgesics for acute pain management: A narrative review
British Journal of Clinical Pharmacology, EarlyView.Combining nonprescription analgesics with different mechanisms of action has been proposed as a rational strategy to optimize the management of acute pain. This review assessed the efficacy and safety of nonprescription analgesics, including paracetamol (acetaminophen), metamizole and nonsteroidal anti‐inflammatory drugs (NSAIDs) used in combination vs.
Ali Mobasheri +5 more
wiley +1 more source
BMC PsychiatryBackground There are progressively alarming rates of non-medical use, addiction and possible dependence on tramadol in low-middle-income countries.
Joseph Lasong +2 more
doaj +1 more source
Bagcilar Medical Bulletin, 2021 Objective:Various strategies of multimodal analgesia exist for pain control following caesarean section, aiming to improve analgesia, reduce opioid requirement, and therefore decrease the incidence of opioid related side effects.
Savas Comlek
doaj +1 more source
Chemistry &Biodiversity, EarlyView.Abstract An infusion of Ageratina grandifolia, a traditional preparation, and major compounds [3,5‐diprenyl‐4‐hydroxyacetophenone (1), O‐methylencecalinol (2), encecalin (3), and encecalinol (4)], tested at 10, 31.6, and 100 mg/kg, intragastrically administered, showed a significant antinociceptive effect in both phases of the formalin test in mice ...
José Alberto Gutiérrez‐González +5 more
wiley +1 more source
PLoS ONE, 2021 Tramadol is used as an analgesic in humans and some animal species. When tramadol is administered to most species it undergoes metabolism to its main metabolites M1 or O-desmethyltramadol, and M2 or N-desmethyltramadol, and many other metabolites.
Benjamin Kimble +3 more
doaj +1 more source
Advances in Ligand‐Driven Pd‐Catalyzed C─H Functionalizations: Recent Insights and Updates
ChemCatChem, EarlyView.The most significant advances in ligand‐driven Pd‐catalyzed organic synthesis over the past two years are presented. Processes involving C─H activation of substrates, avoiding their prefunctionalization are illustrated. Both the activity and selectivity of the catalyst depend on the design of the ligands (pyridones, pyridines, amino acids, phosphines ...
Jesús Moradell +3 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Barriers to incorporating pharmacogenetics into routine clinical practice in the United States are well documented. Initial surveys by the Clinical Pharmacogenetics Implementation Consortium (CPIC) in 2009 and 2010 identified barriers across four key domains that have hindered the widespread adoption of clinical pharmacogenetic testing.
D. Max Smith +18 more
wiley +1 more source