Results 71 to 80 of about 67,803 (253)
British Journal of Clinical Pharmacology, EarlyView.Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar +5 more
wiley +1 more source
Jurnal Kedokteran Diponegoro, 2017 Latar Belakang : Kombinasi parasetamol dan tramadol merupakan analgesik kombinasi yang ideal dan efektif dalam menangani nyeri derajat sedang sampai berat. Keduanya bekerja pada mekanisme berbeda dalam penangan nyeri.
Peggy Rahmat Syahputra +1 more
doaj +1 more source
PLoS ONE, 2021 Tramadol is used as an analgesic in humans and some animal species. When tramadol is administered to most species it undergoes metabolism to its main metabolites M1 or O-desmethyltramadol, and M2 or N-desmethyltramadol, and many other metabolites.
Benjamin Kimble +3 more
doaj +1 more source
PENGARUH PEMBERIAN ANALGESIK KOMBINASI PARASETAMOL DAN TRAMADOL TERHADAP KADAR SERUM GLUTAMAT PIRUVAT TRANSAMINASE TIKUS WISTAR [PDF]
, 2017 Latar Belakang : Kombinasi parasetamol dan tramadol merupakan analgesik kombinasi yang ideal dan efektif dalam menangani nyeri derajat sedang sampai berat. Keduanya bekerja pada mekanisme berbeda dalam penangan nyeri.
Nugroho, Taufik Eko +1 more
core
Prescribing patterns of tramadol in adults in IMS® primary care databases in France and Germany between 1 January 2006 and 30 June 2016 [PDF]
, 2019 Purpose There is increasing concern with regard to fatal intoxications with prescription opioids and tramadol poisonings. This study aimed to characterise prescribing patterns for tramadol in primary care in France and Germany and identify long-term ...
Hedenmalm, Karin +4 more
core +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo +8 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Drug Testing and Analysis, EarlyView.Concentration ranges, dose–concentration relationships, and metabolite‐to‐parent drug ratios of therapeutic opioids were evaluated in hair and skin swab samples of 150 pediatric patients. Skin‐derived matrices such as sweat or sebum were shown to contribute to analyte incorporation into hair in a systematic manner.
Max Polke +7 more
wiley +1 more source
Indian Journal of Pain, 2017 Background: Different techniques are used to provide postoperative pain relief to the patients. The patient-controlled analgesia (PCA) has come out as promising option.
Neeta Abhay Kavishvar +1 more
doaj +1 more source
Comparison of opioid prescribing by dentists in the United States and England [PDF]
, 2019 Importance: The United States consumes most of the opioids worldwide despite representing a small portion of the world\u27s population. Dentists are one of the most frequent US prescribers of opioids despite data suggesting that nonopioid analgesics are ...
Calip, Gregory S +7 more
core +1 more source