Results 111 to 120 of about 19,369 (169)

PROTAC-mediated degradation of Bcl-xL potentiates target therapy in preclinical melanoma models. [PDF]

J Exp Clin Cancer Res
Valentini E, Gentile G, Di Martile M, D'Aguanno S, Brignone M, Di Stefano AM, Di Caprio M, Melucci E, Botti C, Pelle F, Ortolano A, Fattore L, Mancini R, Ciliberto G, Rotili D, Del Bufalo D.   +15 more
europepmc   +1 more source

Inhibition of the JAK and MEK Pathways Limits Mitochondrial ROS Production in Human Saphenous Vein Smooth Muscle Cells. [PDF]

Cells
Bolanle IO, Hobkirk JP, Loubani M, Sturmey RG, Palmer TM.   +4 more
europepmc   +1 more source

Structure-Selective Polydopamine Coating on Drug Nanoparticles. [PDF]

ACS Appl Mater Interfaces
Niezni D, Azagury DM, Avrashami M, Bar-Natan O, Shamay Y.   +4 more
europepmc   +1 more source

Updated result from the phase 2 PHAROS study: has the sustained efficacy and tolerability of encorafenib plus binimetinib been demonstrated in patients with <i>BRAF</i> V600E-mutant metastatic non-small-cell lung cancer? [PDF]

J Thorac Dis
Yonesaka K.
europepmc   +1 more source

Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations. [PDF]

Signal Transduct Target Ther
Hafner P, Keller SJ, Chen X, Alrawashdeh A, Jumaa H, Nollmann FI, Besson S, Kemming J, Gorka O, Das T, Appiah B, Lehmann A, Li M, Apostolova P, Bengsch B, Zeiser R, Tholen S, Schilling O, Groß O, Vlachos A, Wittel UA, von Elverfeldt D, Reichardt W, Boerries M, Andrieux G, Heynen GJ, Fichtner-Feigl S, Hannibal L, Ruess DA.   +28 more
europepmc   +1 more source

Durable disease control in a radiation-induced high-grade glioma harboring <i>NF1</i> and <i>PTPN11</i> co-mutations. [PDF]

Neurooncol Adv
Sherief M, Fatteh M, Wehr J, Holdhoff M, Eberhart CG, Anagnostou V, Schreck KC.   +6 more
europepmc   +1 more source

Trametinib Thwarts Activation of Survival Pathways Induced by Pro-ferroptotic Drug Conjugate ACXT-3102 Resulting in Enhanced Pancreatic Cancer Cell Death. [PDF]

Mol Cancer Ther
Bishnupuri KS, Newcomer KF, Gong Q, Takchi R, Ye L, Vangveravong S, Ross L, Van Tine BA, Hawkins WG, Spitzer D.   +9 more
europepmc   +1 more source

Successful Treatment of BRAF-Mutated Metastatic Melanoma in an Advanced-Age Patient with Dabrafenib and Trametinib: A Case Report and Literature Review. [PDF]

Case Rep Oncol
Kim CS, Kim JJ, Oh SB.
europepmc   +1 more source

Dabrafenib plus trametinib in an elderly patient with BRAF V600E-mutant advanced pancreatic adenocarcinoma: A case report. [PDF]

Front Oncol
Liu L, Zhu X, Guo Y, Tang M, Zhou W, Chen B.   +5 more
europepmc   +1 more source

Delayed Neurologic Response to Dabrafenib and Trametinib in the Case of Mixed Histiocytosis (LCH/ECD): Case Report and Literature Review. [PDF]

Reports (MDPI)
Imashuku S, Kobayashi M, Miyoshi T, Anzai N.   +3 more
europepmc   +1 more source