Results 91 to 100 of about 21,301 (157)

MEK inhibitors in NF1-associated high-grade glioma: partial responses and outcomes from a single-institution cohort and literature review. [PDF]

J Neurooncol
Yu MC, Hsi AH, Adnan A, Knight SR, McCutcheon IE, Slopis JM, Kamiya-Matsuoka C.   +6 more
europepmc   +1 more source

Quantitative systems pharmacology modeling of class I-III BRAF-mutant NSCLC enables subgroup treatment analysis and combination therapy design. [PDF]

iScience
Hu J, Rao Q, Li Z, Li G, Bi Z, Wen D, Zhao C, Zhou G.   +7 more
europepmc   +1 more source

Preterm Noonan syndrome with generalised venolymphatic malformation. [PDF]

Arch Dis Child Fetal Neonatal Ed
Winkler M, Baik-Schneditz N, Benesch M, Jauch SF, Schwaberger B.   +4 more
europepmc   +1 more source

Brief Report: Combination Capmatinib and Trametinib in Metastatic MET-Driven NSCLC. [PDF]

JTO Clin Res Rep
Brown T, Lara MS, Jiang F, Garon EB, Goldman JW, Riess JW, Blakely CM.   +6 more
europepmc   +1 more source

Post-transplant BRAF/MEK inhibitor maintenance sustains complete remission in BRAF V600E-mutant histiocytic sarcoma. [PDF]

Ann Hematol
Karim I, Arnold T, Bräuninger A, Dohse M, Schell F, Samra MA, Tarawneh T, Burchert A, Gattenlöhner S, Sohlbach K.   +9 more
europepmc   +1 more source

MAPK-driven MYC/p21 axis controls senescence bypass and BCL-XL dependence in vincristine-resistant rhabdomyosarcoma. [PDF]

iScience
Wang Y, Largent AD, Lee D, Modi P, Wang L, Bandhlish A, Ignatius M, Chen EY.   +7 more
europepmc   +1 more source

TRAM-01: A phase 2 study of trametinib for pediatric patients with neurofibromatosis type 1 and plexiform neurofibromas. [PDF]

Neuro Oncol
Sadat Kiaei D, Caru M, Larouche V, Clini E, Pugalenthi Saravanan D, Lippé S, Théoret Y, Décarie JC, Tabori U, Hawkins C, Ellezam B, Ospina LH, Desjardins L, Métras MÉ, Sultan S, Cantin É, Routhier MÈ, Mailloux C, Bertrand MC, Estephan K, McKeown T, Vairy S, Legault G, Renzi S, Bouffet É, Ramaswamy V, Coltin H, Lafay-Cousin L, Hukin J, Alves M, Rent T, Erker C, Jabado N, Dehaes M, Perreault S.   +34 more
europepmc   +1 more source

Mutations to Medicine: Advances in Medical Management of Paediatric, Adolescent, and Young Adult Low-Grade Gliomas. [PDF]

Cancers (Basel)
Burns I, Bennett J.
europepmc   +1 more source

Reactivation of DRP1 plays a functional role in resistance to MEK inhibition in pancreatic cancer cells. [PDF]

Br J Cancer
Sharmin S, Kashatus JA, Adair SJ, Loewgren EB, Fallahi-Sichani M, Bauer TW, Kashatus DF.   +6 more
europepmc   +1 more source

Practical management of BRAF inhibitors in glioma: toxicity and resistance. [PDF]

CNS Oncol
Bazer D, Ayanlaja AA, Schreck KC.
europepmc   +1 more source