Results 111 to 120 of about 21,301 (157)

Metastatic Testicular Germ Cell Tumor in a Patient With Neurofibromatosis Type 1: Treatment With Trametinib Based on <i>NF1</i> Gene Mutation. [PDF]

IJU Case Rep
Goto K, Kijima T, Sato Y, Watanabe K, Kage H, Oda K, Shimoi T, Ishida K, Kume H, Kamai T.   +9 more
europepmc   +1 more source

JAK and MEK Pathway Regulation of Mitochondrial Activity as Possible Targets for Saphenous Vein Smooth Muscle Cell Dysfunction in Diabetes. [PDF]

Cells
Bolanle IO, Moshapa FT, Durham GA, Hobkirk JP, Riches-Suman K, Loubani M, Sturmey RG, Palmer TM.   +7 more
europepmc   +1 more source

Targeting ABL kinases overcomes melanoma immune evasion following resistance to MAPK inhibition. [PDF]

Nat Commun
Tripathi R, Kalal BS, Soni S, Boothe C, Lyon A, Meeks C, He D, Cheng PF, Levesque MP, Liu J, Wang C, Plattner R.   +11 more
europepmc   +1 more source

Outcome of treatment with trametinib in adults with histiocytic neoplasms in the United Kingdom. [PDF]

Br J Haematol
Amerikanou R, Munir T, Bowles K, McNamara C, Chavda N, Price E, Adiyodi J, Coles A, Kelsey P, Smith J, Adams R, Hussein H, Zhao R, Nguyen T, Collin M, Gohil S.   +15 more
europepmc   +1 more source

Novel Use of Mavacamten in RAF1-Associated Noonan Syndrome With Hypertrophic Cardiomyopathy. [PDF]

JACC Case Rep
Ziauddin L, Davidson E, Spears H, Coffman E, McNutt M, Hendren N, Kearney K, Hegde SM, Grodin JL, Tapaskar N.   +9 more
europepmc   +1 more source

Benefits and challenges of adding BKM120 to a BI-3406 plus trametinib combination therapy. [PDF]

BMC Cancer
Schulz B, Leitner E, Rabierad M, Khan MI, Ehlers L, Murua Escobar H, Jaster R, Vollmar B, Zechner D.   +8 more
europepmc   +1 more source

Protocol for Measuring Drug-Target Engagement in Mouse Colorectal Cancer Organoids Using NanoBRET Assay. [PDF]

Bio Protoc
Badmos HA, Steele C, Cagan R.
europepmc   +1 more source

Effects of CDDO‑TFEA on non‑small cell lung cancer growth, apoptosis, and stemness via the MEK/ERK pathway. [PDF]

J Cancer Res Clin Oncol
Lee JY, Chung CL, Tseng TT, Kuo SH, Liu YP, Wu MT, Tsai HP, Kwan AL.   +7 more
europepmc   +1 more source

Redifferentiation-enabled TSHRCART cells overcome antigen loss in aggressive thyroid cancers. [PDF]

Mol Cancer
Manriquez-Roman C, Siegler EL, Gleba JJ, Huynh TN, DeFranco GE, Demirer AA, Pawlush ML, Redig M, Klinge SM, Mai LK, Miller JL, Miller EE, Kimball BL, Tapper EE, Sakemura RL, Stewart CM, Can I, Sirpilla OL, Feigin JM, Yun K, Gutierrez-Ruiz OL, Xia H, Hefazi M, Schick KJ, Ogbodo EJ, Olivier G, Qiu Y, Smallridge RC, Zubair A, Tun HW, Copland JA, Kenderian SS.   +31 more
europepmc   +1 more source