Results 81 to 90 of about 5,120,986 (304)

Efficacy and safety of tranexamic acid in the treatment of adult melasma: An updated meta‐analysis of randomized controlled trials

Journal of Clinical Pharmacy and Therapeutics, 2021
Tranexamic acid (TXA) is a novel treatment option for melasma; however, no consensus exists on its use. This study evaluates the efficacy and safety of TXA for melasma.
Xiaowei Feng, H. Su, Jinwei Xie
semanticscholar   +1 more source

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon, Victoria R. Wong, Samuelson E. Osifo, Timothy Edwards, Himanshu Rao, Jewelia Rempuszewski, Andrew J. Frear, Shaan Sadhwani, Neel B. Shah, Kenneth L. Urish   +9 more
wiley   +1 more source

Effectiveness of preoperative tranexamic acid in reducing blood loss during caesarean section at Aminu Kano Teaching Hospital, Kano: a randomized controlled trial

The Pan African Medical Journal, 2021
Introduction bleeding during and after caesarean section is one of the contributors to maternal mortality and morbidity. Tranexamic acid can be given before surgery to significantly reduce the amount of blood loss during caesarean section.
R. Oseni, Mohammad Zakari, N. Adamou, U. Umar   +3 more
semanticscholar   +1 more source

Preoperative knee joint hypothermia reduces inflammation and recovery time and increases range of motion after total knee arthroplasty: A randomized controlled trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Cryotherapy modulates synovial fluid composition by reducing inflammatory mediators and altering metabolite concentrations, resulting in both anti‐inflammatory and anti‐oxidative effects. The aim was to investigate whether preoperative cryocompression would (1) maintain deep tissue hypothermia during the surgical procedure, (2 ...
Leonardo Pieri, Filippo Leggieri, Dimitri Bartoli, Marco Ponti, Chiara Caparrini, Andrea Baldini   +5 more
wiley   +1 more source

A randomized control trial to evaluate the effectiveness of intravenous, intra-articular and topical wash regimes of tranexamic acid in primary total knee arthroplasty

Journal of Orthopaedic Surgery, 2017
Background: The efficacy of tranexamic acid to decrease post-operative blood loss and blood transfusion is well established in literature. However, the ideal mode of administration is debatable.
Jatin Prakash, Jong-Keun Seon, Yong Jin Park, Cheng Jin, Eun-Kyoo Song   +4 more
doaj   +1 more source

Reducing blood loss during open myomectomy with intravenous versus topical tranexamic acid: A double-blinded randomized placebo-controlled trial

Middle East Fertility Society Journal, 2018
Objectives: To assess the effect of Intravenous versus Topical Tranexamic acid in reducing intra-operative and post-operative blood loss in abdominal myomectomy surgeries.
Nahla W. Shady, Hany F. Sallam, Huda Fahmy   +2 more
doaj   +1 more source

Robotic arm‐assisted total knee arthroplasty reduces postoperative inflammatory response and blood loss compared to manual total knee arthroplasty: A matched‐pairs analysis of 688 patients

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Robotic arm‐assisted total knee arthroplasty (raTKA) has demonstrated several advantages over manual TKA (mTKA), including enhanced early recovery. Reduced soft tissue trauma and avoidance of femoral intramedullary canal opening have been hypothesised to lower the systemic inflammatory response.
Dirk Müller, Igor Lazic, Benjamin Schloßmacher, Vincent Lallinger, Michael T. Hirschmann, Rüdiger von Eisenhart‐Rothe, Florian Pohlig   +6 more
wiley   +1 more source

Topical tranexamic acid improves the permeability barrier in rosacea

Dermatologica Sinica, 2015
Objective: To evaluate the influence of tranexamic acid on epidermal permeability barrier function in rosacea and its potential mechanisms. Methods: A randomized, vehicle controlled, split-face study was performed on 30 rosacea patients.
Shaomin Zhong, Nan Sun, Huixian Liu, Yueqing Niu, Can Chen, Yan Wu   +5 more
doaj   +1 more source

The effect of tranexamic acid on blood loss and maternal outcome in the treatment of persistent postpartum hemorrhage: A nationwide retrospective cohort study. [PDF]

PLoS ONE, 2017
Recent results show a protective effect of tranexamic acid on death due to bleeding in patients with postpartum hemorrhage in low- and middle-resource countries. We quantify the association between early administration of tranexamic acid compared to late
Ada Gillissen, Dacia D C A Henriquez, Thomas van den Akker, Camila Caram-Deelder, Merlijn Wind, Joost J Zwart, Jos van Roosmalen, Jeroen Eikenboom, Kitty W M Bloemenkamp, Johanna G van der Bom, TeMpOH-1 study group   +10 more
doaj   +1 more source

WOMAN-2 Pilot Study Data [PDF]

, 2019
Data and supporting material produced as part of a pilot study to test outcome questions for the WOMAN-2 trial of tranexamic acid for the prevention of postpartum haemorrhage.
Beaumont, Danielle, Brenner, Amy, Chaudhri, Rizwana, Chaudhri, Shahana, Edwards, Phil, Javaid, Kiran, Kayani, Aasia, Miller, Lori, Roberts, Ian, Shakur-still, Haleema   +9 more
core   +1 more source