Results 201 to 210 of about 3,929,670 (363)

Exploring the effect of activator topology on CRISPR-Cas12a trans-cleavage activity. [PDF]

Nucleic Acids Res
Zhu Z, Li X, Ding L, Wu T.
europepmc   +1 more source

trans activation of rat phosphoenolpyruvate carboxykinase (GTP) gene expression by micro-coinjection of rat liver mRNA in Xenopus laevis oocytes.

, 1989
Nissim Benvenisty, Tzipora Shoshani, Yigal Farkash, Hermona Soreq, Lea Reshef   +4 more
openalex   +1 more source

Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains [PDF]

, 1990
R M Stenberg, James Fortney, S W Barlow, B P Magrane, Jay A. Nelson, Peter Ghazal   +5 more
openalex   +1 more source

Mechanochemistry: Fundamental Principles and Applications

Advanced Science, EarlyView.
In this review, the physicochemical principles of mechanochemistry are first clarified. Based on this foundation, the research basis and cutting‐edge scientific achievements in four areas are introduced: solid‐state organic chemistry, polymers, interface science, and biomechanochemistry.
Liang Dong, Luofei Li, Huiyan Chen, Yi Cao, Hai Lei   +4 more
wiley   +1 more source

Precise amplification-free detection of highly structured RNA with an enhanced SCas12a assay. [PDF]

Commun Biol
Zhang J, Yin W, Jiang Q, Mao W, Deng W, Jin S, Wang X, He R, Qiao J, Liu Y.   +9 more
europepmc   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Regulation of CRISPR trans-cleavage activity by an overhanging activator. [PDF]

Nucleic Acids Res
Yin N, Yu H, Zhang L, Luo F, Wang W, Han X, He Y, Zhang Y, Wu Y, Pu J, Feng T, Yang G, Chen T, Xie G.   +13 more
europepmc   +1 more source

Role of E2F transcription factor in E1A-mediated trans activation of cellular genes [PDF]

, 1991
Scott W. Hiebert, M Blake, J Azizkhan, Joseph R. Nevins   +3 more
openalex   +1 more source

The product of the c‐ets‐1 proto‐oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV‐1.

EMBO Journal, 1990
'. RemyBosselut, J. Duvall, A. Gégonne, '. ManuellaBailly, A. Hémar, J. Brady, Jacques Ghysdaell   +6 more
semanticscholar   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source