Results 91 to 100 of about 6,216 (203)
Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer’s Disease
Molecules, 2018 Alzheimer’s disease still represents an untreated multifaceted pathology, and drugs able to stop or reverse its progression are urgently needed.
Angela Rampa +9 more
doaj +1 more source
Development of a Fragment-Based in Silico Profiler for Michael Addition Thiol Reactivity [PDF]
The Adverse Outcome Pathway (AOP) paradigm details the existing knowledge that links the initial interaction between a chemical and a biological system, termed the molecular initiating event (MIE), through a series of intermediate events, to an adverse ...
Cronin, MTD +4 more
core +1 more source
종양 발생 과정에서 NAG-1 (GDF15)과 TSP-1의 바이오마커 및 치료 타겟으로써의 유용성 연구 [PDF]
, 2023 학위논문(박사) -- 서울대학교대학원 : 수의과대학 수의학과, 2023. 8. 백승준.암은 세계적으로 가장 중요한 공중보건 문제 중 하나로, 환자 사망률에 큰 영향을 미친다. 인간과 반려 동물 모두에서 암의 발생률은 점점 증가해왔으며, 생존율 증가를 위해 암의 조기 발견 및 정확한 진단이 환자 예후 개선에 매우 중요하다. 따라서, 지난 몇 십 년 동안 암의 조기 발견과 예후 평가에 기여할 수 있는 바이오마커를 발굴하기 위한 다양한 연구들이 진행되었다.
홍유경
core
Citrus reticulata Blanco: A Review on Chemical Composition and Biological Activities
Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.This review compiles chemical information and biological activities from 49 studies on Citrus reticulata. The fruit peels stand out for their high content of methoxylated monoterpenes and flavonoids with antioxidant, anti‐inflammatory, and antimicrobial activities.
José Walber Gonçalves Castro +3 more
wiley +1 more source
ChemSusChem, Volume 19, Issue 1, January 2026.Iron coordinated on silk fibroin from Bombyx mori is easily prepared and catalyzes olefin epoxidation under mild, sustainable conditions with O2. With minimal iron loading, the catalyst is highly recyclable and fully regenerable, offering a green route to heterogeneous catalysis.
Carola Ricciardelli +8 more
wiley +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2019 The molecular structure of the title chalcone derivative, C15H10FNO3, is nearly planar and the molecule adopts a trans configuration with respect to the C=C double bond.
Qin Ai Wong +5 more
doaj +1 more source
Food Frontiers, Volume 7, Issue 1, January 2026.The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima +15 more
wiley +1 more source
(E)-1-(5-Chlorothiophen-2-yl)-3-(p-tolyl)prop-2-en-1-one
IUCrData, 2017 In the title compound, C14H11ClOS, the trans conformation of the C=C double bond in the central enone group is confirmed by the C—C=C—C torsion angle of 178.3 (4)°.
Karthik Kumara +5 more
doaj +1 more source
Chalcones in Dermatology [PDF]
, 2020 The human skin is pivotal for protecting the body from various stresses and diseases, regulating several physiological aspects, and sensing any signal changes around the environment.
Harizal, +2 more
core +2 more sources
Imaging of Molecular and Developmental Responses to Abiotic Stresses in Reproductive Tissues
Physiologia Plantarum, Volume 178, Issue 1, January/February 2026.ABSTRACT Abiotic stresses, such as drought, salinity, and extreme temperatures, have profound effects on plant reproduction, often leading to reduced fertility and yield. Reproduction in plants involves complex interactions between diverse cells, necessitating spatiotemporal resolution to understand how stress impacts each component of this intricate ...
Hana Daryanavard +7 more
wiley +1 more source