Crystal structure of (E)-3-(2-hydroxy-4-methylphenyl)-1-(2,4,6-trimethoxyphenyl)prop-2-en-1-one
The title chalcone derivative, C19H20O5, adopts a trans configuration with respect to the olefinic C=C double bond. The 2-hydroxy-4-methylphenyl ring is coplanar with the attached enone bridge [torsion angle = −179.96 (14)°], where this plane is nearly ...
Maadh Jumaah +2 more
doaj +1 more source
Synthesis, Characterization, Antioxidant Activity and Conformational Study of 4-Hydroxychalcone
The objective of this work was to develop a synthesis, characterization, and conformational study of 4-hydroxychalcone. The chalcone was obtained using Claisen-Schmidt reaction. The product was characterized by IR and NMR spectroscopy.
André Luis Kerek +2 more
doaj +3 more sources
(E)-3-(4-Bromophenyl)-1-(3,4-dichlorophenyl)prop-2-en-1-one
The molecule of the title compound, C15H9BrCl2O, is shown to be the E isomer, with the 3,4-dichlorobenzoyl and p-bromophenyl substituents in trans positions with respect to the chalcone olefin bond.
Rajni Kant +4 more
doaj +1 more source
In Vitro Action of Flavonoids in the Canine Malignant Histiocytic Cell Line DH82
Cancer is commonly diagnosed in dogs over the age of 10 and is a leading cause of death due to the lack of effective drugs. Flavonoids possess antioxidant, anti-inflammatory and anticarcinogenic properties and have been studied as chemopreventive agents ...
Gabriel Silva +4 more
doaj +1 more source
Natural and Synthetic Flavylium-Based Dyes: The Chemistry behind the Color [PDF]
Funding Information: This research was supported by project grants (PTDC/OCE-ETA/31250/2017; PTDC/QUI-COL/32351/2017), with financial support from FCT/MEC through national funds and cofinancing from FEDER, in Partnership Agreement PT2020 (UIDB/50006/2020
Basílio, Nuno +4 more
core +1 more source
A Way to Improve Luminescent Efficiency of Bis-Chalcone Derivatives
Chalcone related compounds have been reported as a poor luminescence molecule due to the quenching processes from the intramolecular torsional motions and cis-trans isomerization in the α,β-unsaturated ketone moiety.
Meng Guan Tay +4 more
doaj +1 more source
(E)-3-(2,4-Dimethoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
In the title chalcone derivative, C20H22O6, the dihedral angle between the mean planes of the benzene rings is 15.77 (6)°. The H atoms of the central C=C double bond are in a trans configuration. There are a number of C—H...O
Jianzhang Wu +4 more
doaj +1 more source
Bio-Evaluation of 99mTc-Labeled Homodimeric Chalcone Derivative as Amyloid-β-Targeting Probe
Chalcone derivatives have been successfully utilized for a range of biological applications and can cross the blood–brain barrier easily. β-amyloid-specific bis-chalcone derivative, 6,9-bis(carboxymethyl)-14-(4-[(E)-3-(4-(dimethylamino)phenyl)acryloyl ...
Garima Mann +7 more
doaj +1 more source
Nagy pontosságú számítások az elméleti kémiában: módszerfejlesztés és alkalmazás = High-accuracy calculations in theoretical chemistry: method development and application [PDF]
Kutatásaink legfontosabb eredménye olyan nagy pontosságú elméleti módszerek kifejlesztése, amelyek alacsonyabb számításigénnyel rendelkeznek, mint a korábban használt módszerek, de pontosságuk nem marad el az utóbbiak mögött.
Kállay, Mihály
core
Non-alcoholic steatohepatitis (NASH) is an inflammatory and progressive form of non-alcoholic fatty liver disease. However, there are no FDA-approved drugs for this condition. Lipids accumulated in NASH have a direct role in the progression of this disease.
Elham, Karimi-Sales +2 more
openaire +2 more sources

