Results 51 to 60 of about 736,450 (179)

University teaching of mass spectrometry as a key practical technique within the context of a fully integrated, spiral curriculum

Rapid Communications in Mass Spectrometry, EarlyView.
Rationale Mass spectrometry (MS) is introduced to high school students in the UK in many pre‐university course syllabi. As such, we have identified the use of MS as a key technique that should be taught practically to undergraduates from the outset of their studies.
Andrew F. Worrall, Craig D. Campbell, Megan O. Midson, Malcolm I. Stewart   +3 more
wiley   +1 more source

In Vitro Action of Flavonoids in the Canine Malignant Histiocytic Cell Line DH82

Molecules, 2013
Cancer is commonly diagnosed in dogs over the age of 10 and is a leading cause of death due to the lack of effective drugs. Flavonoids possess antioxidant, anti-inflammatory and anticarcinogenic properties and have been studied as chemopreventive agents ...
Gabriel Silva, Ana Lúcia Fachin, Renê O. Beleboni, Suzelei C. França, Mozart Marins   +4 more
doaj   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change

Journal of Integrative Plant Biology, EarlyView.
This review covers recent progress in the understanding of stress‐responsive regulatory networks in soybean and highlights emerging genomic and breeding strategies. Integrating molecular insights and precision breeding will help to accelerate the development of climate‐resilient soybean cultivars.
Ali Shahzad, Monan Sun, Shuangkang Pei, Xiaoyu Liu, Yinhe Zhang, Keheng Xu, Hongtao Gao, Yonggang Zhou, Haiyan Li   +8 more
wiley   +1 more source

(E)-3-(2,4-Dimethoxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one

Acta Crystallographica Section E, 2012
In the title chalcone derivative, C20H22O6, the dihedral angle between the mean planes of the benzene rings is 15.77 (6)°. The H atoms of the central C=C double bond are in a trans configuration. There are a number of C—H...O
Jianzhang Wu, Junyan Qiu, Xiaokai Wu, Shulin Yang, Yonggen Liu   +4 more
doaj   +1 more source

Bio-Evaluation of 99mTc-Labeled Homodimeric Chalcone Derivative as Amyloid-β-Targeting Probe

Frontiers in Medicine, 2022
Chalcone derivatives have been successfully utilized for a range of biological applications and can cross the blood–brain barrier easily. β-amyloid-specific bis-chalcone derivative, 6,9-bis(carboxymethyl)-14-(4-[(E)-3-(4-(dimethylamino)phenyl)acryloyl ...
Garima Mann, Garima Mann, Kanchan Chauhan, Vikas Kumar, Shivani Daksh, Nikhil Kumar, M. Thirumal, Anupama Datta   +7 more
doaj   +1 more source

Neuroprotective Role of Transchalcone in Parkinson‘s Disease through AMP-activated Protein Kinase-mediated Signaling Pathway

Journal of Physiological Investigation
Parkinson’s disease (PD) is a gradually worsening neurodegenerative condition marked by the deterioration of dopaminergic neurons, motor dysfunction, and mitochondrial dysfunction. Trans-chalcone, a natural flavonoid, has shown promise in various disease
Yao Cheng, Shaik Althaf Hussain, Turki Mayudh Alrubie, Xiaomin Zhang   +3 more
doaj   +1 more source

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

(2E,2′E)-1,1′-(1,4-Phenylene)bis[3-(3-chlorophenyl)prop-2-en-1-one]

IUCrData, 2017
The title bis-chalcone compound, C24H16Cl2O2, crystallizes with one half-molecule in the asymmetric unit. The molecule has crystallographic inversion symmetry and lies about an inversion centre at the centroid of the central benzene ring.
S. Rajendraprasad, C. S. Chidan Kumar, S. Chandraju, N. K. Lokanath, Ching Kheng Quah, S. Naveen, Muneer Abdoh   +6 more
doaj   +1 more source

Development of chalcones structure‐related to avobenzone: Photoprotection, photostability, and safety evaluation

Photochemistry and Photobiology, EarlyView.
Scaffold hopping strategy used to develop chalcones structure‐related to the avobenzone tautomer. Positive aspects of 2‐hydroxychalcones are highlighted. Abstract Chalcones are α,β‐unsaturated ketones with extended π‐conjugation, making them promising scaffolds for the development of organic UV filters.
Gabriela Zanella Marcon, Taíne de Bastos Brum, Nayara Fernanda Tokashike de Araujo, Gabriela Lascala Ramos, Bruna Cogo Borin, Ruth Barin, Aline Ferreira Ourique, André Passaglia Schuch, Andréa Inês Horn Adams, Lorena Rigo Gaspar Cordeiro, Letícia Cruz, Fernando Fumagalli   +11 more
wiley   +1 more source