Results 31 to 40 of about 873,934 (176)

Trans-Chalcone Reduces Inflammation and Pain Triggered by Superoxide Anion: Neuronal and Non-Neuronal Mechanisms [PDF]

Journal of Inflammation Research
Maiara Piva,1 Marília F Manchope,1,2 Fernanda Barbosa-Costa,1 Beatriz H S Bianchini,1 Ketlem C Andrade,1 Letícia Coelho Silva,1 Cássia Calixto-Campos,1 Fernanda S Rasquel-Oliveira,1,3 Victor Fattori,1,3 Ana Carla Zarpelon-Schutz,1 Doumit Camilios-Neto,4 Sergio M Borghi,1 Rubia Casagrande,5 Waldiceu A Verri1 1Department of Immunology, Parasitology ...
Maiara Piva, Marília Manchope, Fernanda Barbosa-Costa, Beatriz Bianchini, Ketlem Andrade, Letícia Silva, Cássia Calixto-Campos, Fernanda Rasquel-Oliveira, Victor Fattori, Ana Carla Zarpelon-Schutz, Doumit Camilios-Neto, Sergio Borghi, Rubia Casagrande, Waldiceu Verri   +13 more
openaire   +3 more sources

PM6 and PDDG vs. DFT: A Computational Assessment of the Stability of cis and trans para Amino-dichloro Chalcone Isomers.

Zanin Journal of Science and Engineering
Chalcone molecules are well known for their versatile chemical properties and diverse applications in pharmaceuticals and materials science, making their conformational stability vital for understanding their behavior.
Harikar Mohammed Ali, Ghazwan Faisal Fadhil   +1 more
doaj   +3 more sources

Development and validation of a UV–Vis spectrophotometric method for estimation of total content of chalcone

MethodsX
In this study, a straightforward spectrophotometric method was developed for quantifying the total content of chalcones in a sample. The method exhibits linearity, accuracy, precision, repeatability, and enables the estimation of total chalcone content ...
J.R.S. Botelho, A. Caeiro, H.C. Sousa, M.E.M. Braga, M.G. Campos   +4 more
doaj   +2 more sources

A Way to Improve Luminescent Efficiency of Bis-Chalcone Derivatives [PDF]

Journal of Chemistry, 2016
Chalcone related compounds have been reported as a poor luminescence molecule due to the quenching processes from the intramolecular torsional motions and cis-trans isomerization in the α,β-unsaturated ketone moiety.
Meng Guan Tay, Mee Hing Tiong, Ying Ying Chia, Suzie Hui Chin Kuan, Zhi-Qiang Liu   +4 more
doaj   +2 more sources

Trans-Chalcone Plus Baicalein Synergistically Reduce Intracellular Amyloid Beta (Aβ₄₂) and Protect from Aβ₄₂ Induced Oxidative Damage in Yeast Models of Alzheimer's Disease. [PDF]

Int J Mol Sci, 2021
Finding an effective therapeutic to prevent or cure AD has been difficult due to the complexity of the brain and limited experimental models. This study utilized unmodified and genetically modified Saccharomyces cerevisiae as model organisms to find ...
Dhakal S, Ramsland PA, Adhikari B, Macreadie I.   +3 more
europepmc   +2 more sources

Novel chalcone-based fluorescent human histamine H 3 receptor ligands as pharmacological tools [PDF]

, 2012
Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif.
Miriam Tomasch, Lilia Weizel, Weizel, Lilia, Stark, Holger, Tomasch, Miriam, Holger Stark, Schwed, J. Stephan, J. Stephan Schwed   +7 more
core   +1 more source

Figure S6. The ER resident protein DapA does not reallocate in presence of trans-chalcone.

, 2023
Figure S6. The ER resident protein DapA does not reallocate in presence of trans-chalcone. Fluorescence microscopy was performed with the sdeA::GFP and dapA::GFP strain (SJX29, kindly provided by Dr. Ling Liu - Nanjing Normal University, China).
Iran Malavazi (14855818)
core   +1 more source

Induction of Methuosis in Breast Cancer Stem Cells by a Cobalt(III) Complex Evokes Immunotherapeutic Response

Angewandte Chemie, EarlyView.
Cancer stem cells (CSCs) drive metastasis, relapse and resist conventional apoptosis‐inducing chemotherapies. We report a cobalt(III)‐cyclam complex with pyrene and diflunisal moieties that reduces the viability of breast CSCs at low micromolar concentrations.
Jiaxin Fang, Sijie Wen, Xiao Feng, Hao Ren, Kuldip Singh, Haihua Xiao, Lingpu Zhang, Kogularamanan Suntharalingam   +7 more
wiley   +2 more sources

Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone [PDF]

Sortase A (SrtA) from Gram positive pathogens is an attractive target for inhibitors due to its role in the attachment of surface proteins to the cell wall.
Maitra A, Dodds M, Marles-Wright J, Wallock-Richards DJ, Hanley B, Campopiano DJ, Clarke DJ   +6 more
core   +4 more sources

(E)-3-{4,6-Dimethoxy-2-[(E)-4-methoxystyryl]-3-methylphenyl}-1-(2-hydroxy-5-methoxyphenyl)prop-2-en-1-one

IUCrData, 2020
In the title compound, C28H28O6, the benzene rings in the resveratrol moiety are connected by a trans C=C double bond, and the hydroxyl group containing a benzene ring and the central benzene ring are linked through a C=(O)—C=C (enone) moiety to form a ...
Miri Yoo, Dongsoo Koh
doaj   +1 more source