Results 11 to 20 of about 114,148 (343)
Background/Purpose: Nonalcoholic fatty liver disease (NAFLD) constitutes a spectrum of liver diseases associated with various metabolic disorders. Exercise interventions reportedly manage the clinical outcomes of NAFLD, but their efficacy depends on ...
Feng Hong +6 more
semanticscholar +1 more source
Shifting the pH Optima of (R)-Selective Transaminases by Protein Engineering
Amine transaminases (ATAs) are powerful biocatalysts for the stereoselective synthesis of chiral amines. However, wild-type ATAs usually show pH optima at slightly alkaline values and exhibit low catalytic activity under physiological conditions.
Chao Xiang +3 more
semanticscholar +1 more source
Predicting and grading liver injury in the absence of computed tomographic imaging
Background: Even developed countries lack computed tomography (CT) scan in rural areas. Availability, affordability and accessibility of CT scan play an important role in the management of blunt hepatic trauma.
Mario Victor Newton, S. G. Subramanyam
doaj +1 more source
Therapy of acute hepatitis C infection [PDF]
Background. Hepatitis C viral infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The progression of acute to chronic infection occurs in 50-90% of cases.
Đokić Milomir, Begović Vesna
doaj +1 more source
Protein engineering of amine transaminases
Protein engineering is a powerful and widely applied tool for tailoring enzyme properties to meet application-specific requirements. An attractive group of biocatalysts are PLP-dependent amine transaminases which are capable of converting prochiral ...
Qinglong Meng +3 more
semanticscholar +1 more source
Gunshot liver injuries grade I-III and related liver enzyme values [PDF]
Background/Aim. The liver is one of the most commonly injured solid organ in patients with abdominal gunshot wounds. The aim of this study was to investigate correlation between aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels ...
Radunović Miodrag +4 more
doaj +1 more source
Background: Neurological manifestations following dengue fever are increasingly reported and include encephalopathy, encephalitis, neuro-ophthalmic manifestations or Guillain–Barre syndrome-like presentation.
Arpit Mittal +3 more
doaj +1 more source
Antioxidant, hypoglycemic, and hepatoprotective effect of aqueous and ethyl acetate extract of carob honey in streptozotocin -induced diabetic rats [PDF]
Aim: The aim of the study included the effect of aqueous extract (AE) and ethyl acetate extract (EAE) on blood sugar in diabetic rats and their effects on liver enzymes and lipid panel in control and diabetic rats.
Redouan El-Haskoury +4 more
doaj +1 more source
Background Elevations of hepatic transaminase (serum alanine transaminase [ALT] and serum aspartate aminotransferase [AST]) levels in patients with acute coronary syndrome (ACS), although transient, may result in exclusions from clinical efficacy trials ...
Małgorzata Jasiewicz +9 more
semanticscholar +1 more source
Introduction: Given the impact of COVID-19 on the world healthcare system, and the efforts of the healthcare community to find prognostic factors for hospitalization, disease progression, and mortality, the aim of the present study was to investigate the
Antonio Russo +20 more
doaj +1 more source

