Only limited data on laboratory parameter dynamics and safety under prolonged biologic treatment in a “real-world” scenario are available for recommendations on screening and monitoring.
Jochen H. Hoffmann+3 more
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BACKGROUND: Isotretinoin has been used to treat the most severe cases of acne; however, it may provoke adverse events in mucocutaneous and hepatic tissues, lead to alterations in lipid levels and cause teratogenicity.
Andreia Salezze Vieira+2 more
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Hepatotoxicity Evaluation of Aqueous Extract from Scutia buxifolia
Nowadays there is an increase in the number of people taking herbals worldwide. Scutia buxifolia is used for the treatment of hypertension, but little is known about its action on liver.
Margareth Linde Athayde+11 more
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Long-term outcomes of direct acting antivirals in post-transplant advanced hepatitis C virus recurrence and fibrosing cholestatic hepatitis. [PDF]
Long-term functional outcomes of sofosbuvir-based antiviral treatment were evaluated in a cohort study involving 16 Italian centres within the international compassionate use programme for post-transplant hepatitis C virus (HCV) recurrence. Seventy-three
Burra, Patrizia+2 more
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Therapy of acute hepatitis C infection [PDF]
Background. Hepatitis C viral infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The progression of acute to chronic infection occurs in 50-90% of cases.
Đokić Milomir, Begović Vesna
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Evidence of Phenylalanine Transaminase Activity in the Isoenzymes of Aspartate Transaminase
Abstract The transamination by pig mitochondrial and supernatant aspartate transaminase of aromatic amino acids was studied in order to determine if an analogy exists between these enzymes and a previously reported brain phenylalanine transaminase (George, H., and Gabay, S. (1968) Biochim. Biophys. Acta, 167, 555).
Elsie J. Shrawder+1 more
openaire +3 more sources
Rational design of a (S)-selective-transaminase for asymmetric synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine [PDF]
Amine transaminases offer an environmentally sustainable synthesis route for the production of pure chiral amines. However, their catalytic efficiency toward bulky ketone substrates is greatly limited by steric hindrance and therefore presents a great ...
Allen, Christopher C.R.+12 more
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Gunshot liver injuries grade I-III and related liver enzyme values [PDF]
Background/Aim. The liver is one of the most commonly injured solid organ in patients with abdominal gunshot wounds. The aim of this study was to investigate correlation between aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels ...
Radunović Miodrag+4 more
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Branched chain aldehydes: production and breakdown pathways and relevance for flavour in foods [PDF]
Branched aldehydes, such as 2-methyl propanal and 2- and 3-methyl butanal, are important flavour compounds in many food products, both fermented and non-fermented (heat-treated) products. The production and degradation of these aldehydes from amino acids
Engels, W.J.M., Smit, B.A., Smit, G.
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EFFECT OF PIGEON ORIGIN NEWCASTLE DISEASE VIRUS ON VARIOUS LIVER ENZYMES AND ASSOCIATED PATHOLOGICAL CHANGES IN EXPERIMENTALLY INFECTED PIGEONS [PDF]
Newcastle disease virus (NDV) was isolated from a field outbreak in pigeons. The virus was characterized by haemagglutination test (HA) and confirmed by haemagglutination inhibition test (HAI).
I. MUSHTAQ, F. RIZVI AND M. S. ULLAH
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